Hip fractures in Parkinson’s Disease: A single-centre retrospective cohort study
Objective: Evaluate hip fracture (NOF) management in Parkinson's (PD) against National Institute of Clinical Excellence (NICE) guidelines to identify if adverse outcomes arise from differences…Sleep Disorders and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To comprehensively evaluate the association between various sleep disorders and the risk of developing Parkinson’s disease. Background: Sleep disturbances are increasingly recognized as important…Ante-Mortem Motor Speech Profiles in Postmortem Confirmed Atypical Parkinsonisms
Objective: Differences in motor speech profiles may aid in diagnosis of atypical parkinsonisms. This is a retrospective study that characterizes ante-mortem motor speech profiles in postmortem…Topographic Heterogeneity of Dopaminergic Denervation and Iron Deposition in Functional Subregions of Nigrostriatal System in Parkinson’s Disease
Objective: To investigate the spatial relationship between striatal dopaminergic denervation and nigral iron accumulation in Parkinson’s disease (PD) using functional subregional parcellation. Background: Excessive nigral…Cannabis-based Oil for Pain and Other Non-motor Symptoms in Parkinson’s Disease: a Randomized Controlled Trial
Objective: To assess the safety, tolerance, and effectiveness of an oil extract of Cannabis sativa L. on pain and other non-motor symptoms (NMS) in people…The Impact of Demographic Factors on Skull Density Ratios in a Hawaii Cohort
Objective: To understand the impact of demographic factors on skull density ratio (SDR) in Hawai‘i patients. Background: SDR is a validated indicator of the ability…Investigating Phospho-α-Synuclein Pathology in Patient-Specific Microglia Integrated into Midbrain Organoids
Objective: This study aims to determine how patient-specific microglia influence phospho-α‑synuclein aggregation and contribute to disease-relevant phenotypes within human midbrain organoids. Background: Parkinson’s disease (PD)…Posterior tibial nerve Stimulation in the management of Urinary Disorders in Parkinson’s Disease Experience of the National Hospital Center of Pikine
Objective: Evaluate the efficacy of posterior tibial nerve stimulation in the management of LUTS in patients with PDCompare posterior tibial nerve stimulation to medication Background:…Vocal Tremor as the Initial Manifestation of Palatal Tremor with Response to Propranolol : A Case Report
Objective: To describe an unusual presentation of essential palatal tremor manifesting as vocal tremor and to discuss its diagnostic considerations and therapeutic response to propranolol.…Mechanisms of PLA2G6 Deficiency Impacting Mitochondria-associated membranes in Parkinson’s Disease
Objective: This study aims to explore the functions of PLA2G6 protein at the endoplasmic reticulum-mitochondria interface, unveiling the potential mechanisms of PLA2G6-related Parkinson’s disease (PD)…
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