Session Time: 1:45pm-3:15pm
Location: Exhibit Hall C
Objective: The aim of this study was to evaluate the impact of STN DBS on balance disorders in PD patients.
Background: Subthalamic nucleus deep brain stimulation (STN DBS) can influence on balance and gait disorders, but there are some conflicting information.
Methods: DBS-group consisted of 20 PD patients (7F,13M) who underwent bilateral STN DBS. POP-group consisted of 15 post-DBS PD patients (6F,9M) in median 24 month-time after surgery. Control group (MED-group) consisted of 24 patients (13F,11M) who did not underwent surgical intervention. UPDRS III scale and balance tests (UpAndGo Test, Tandem Walk Test) were measured during 3 visits (V1, V2, V3) in total OFF phase. The mean period between visits was 9±3months.
Results: We have observed the improvement in balance tests (UpAndGo, TWT) in V2/V1 DBS-group period (p<0,05) which was not observed in other (MED, POP) groups. The effect was not observed in V3/V2 DBS-group period. The comparable UPDRS III changes were also observed in V2/V1 (p<0,05) vs V3/V2 (p>0,05) DBS-group periods whereas V3/V2/V1 in MED-group and POP-group UPDRS III OFF scores were statistically changed (p<0,05).
Conclusions: STN DBS can temporarily improve balance disorders in PD patients, with the strongest effect during first 6 postoperative months.
To cite this abstract in AMA style:S. Szlufik, M. Kloda, I. Potrzebowska, K. Gregier, A. Friedman, A. Przybyszewski, J. Dutkiewicz, P. Habela, T. Mandat, D. Bialoszewski, D. Koziorowski. STN DBS can temporarily improve balance disorders in Parkinson’s disease (PD) patients. [abstract]. Mov Disord. 2017; 32 (suppl 2). https://www.mdsabstracts.org/abstract/stn-dbs-can-temporarily-improve-balance-disorders-in-parkinsons-disease-pd-patients/. Accessed December 1, 2023.
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MDS Abstracts - https://www.mdsabstracts.org/abstract/stn-dbs-can-temporarily-improve-balance-disorders-in-parkinsons-disease-pd-patients/