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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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The changes in activities of daily livings after deep brain stimulation in Parkinson’s disease

T. Yamamoto, M. Suzuki, S. Hirano, Y. Yamanaka, A. Sugiyama, N. Araki, Y. Higuchi, S. Kuwabara (Chiba, Japan)

Meeting: 2022 International Congress

Abstract Number: 345

Keywords: Deep brain stimulation (DBS), Parkinson’s

Category: Surgical Therapy: Parkinson's Disease

Objective: We aimed to clarify long-term changes in activities of daily living in patients with Parkinson’s disease (PD) who underwent deep brain stimulation (DBS).

Background: It is well known that DBS dramatically alleviates motor complications in PD. However, long-term changes in activities of daily living are not well elucidated.

Method: We retrospectively reviewed seventeen patients with PD (mean age 65.18±1.42 years, mean disease duration 11.94±0.57 years) who underwent subthalamic nucleus (STN)- DBS and completed pre-operative and post-operative (one year and three years after surgery) evaluations. Activities of daily living (ADL) and motor functions were evaluated by Unified Parkinson’s disease Rating Scale (UPDRS) Parts 2 and Parts 3, respectively.

Results: The score of UPDRS-Parts 2 during on phase was significantly increased three years after surgery compared to baseline (6.82±1.32 → 13.29±1.93, p=0.011), whereas the score of UPDRS-Parts 3 during off phase was significantly decreased three years after surgery compared to baseline (39.24±2.91 → 26.71±3.12, p=0.01). Of the seventeen patients, the score of UPDRS-Parts 2 during the on phase increased more than six in eight patients (ADL deteriorated group). The differences in the score of UPDRS-Parts 3 during the off phase between baseline and three years after surgery were significantly reduced in the ADL deteriorated group compared to the no ADL deteriorated group.

Conclusion: Some patients with Parkinson’s disease showed deteriorations of ADL within three years after DBS.

To cite this abstract in AMA style:

T. Yamamoto, M. Suzuki, S. Hirano, Y. Yamanaka, A. Sugiyama, N. Araki, Y. Higuchi, S. Kuwabara. The changes in activities of daily livings after deep brain stimulation in Parkinson’s disease [abstract]. Mov Disord. 2022; 37 (suppl 2). https://www.mdsabstracts.org/abstract/the-changes-in-activities-of-daily-livings-after-deep-brain-stimulation-in-parkinsons-disease/. Accessed July 15, 2025.
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