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Treatment approaches for infection following DBS

F. Yuzbasi, H. Kaptan (Izmir, Turkey)

Meeting: 2019 International Congress

Abstract Number: 2089

Keywords: Deep brain stimulation (DBS)

Session Information

Date: Wednesday, September 25, 2019

Session Title: Surgical Therapy

Session Time: 1:15pm-2:45pm

Location: Les Muses Terrace, Level 3

Objective: We retrospectively reviewed all infection following DBS surgeries performed in a 4-year period

Background: Infection is one of the most common complications of deep brain stimulation (DBS) Device-related infections and erosion of the surgical wound site are special circumstances among complications of  DBS. This is a feared complication, as it is difficult to manage and leads to increased patient morbidity. (1,2,3,)

Method: To study short- and long-term DBS-related infection ; to evaluate treatment associated with 3 patients with device-related infection.

Results: Electrode placement to bilateral subthalamic nuclei  was performed due to Parkinson’s Disease to all 3 patients. One of the patients was undergone surgical wound site revision for six times and device removal at last because of device-related infection and erosion of the surgical wound site. The second patient was undergone surgical wound site revision for two times and device removal at last because of device-related infection and erosion of the surgical wound site. The last patient  had a collection subcutaneously in where the pulse generator placed. Aspiration of the collection was performed. We tried treatment with antibiotics and/or wound revision are a suitable option before the decision of device removal. Unfortunately we did not succeed in one. Of the two patients treated successfully conservatively.

Conclusion: It was our priority to try a conservative approach in surgical site infections related to DBS, in order to avoid unnecessary removal of the hardware.

References: 1.Bhatia R, Dalton A, Richards M, Hopkins C, Aziz T, et al. The incidence of deep brain stimulator hardware infection: the effect of change in antibiotic prophylaxis regimen and review of the literature. Br J Neurosurg 25: 625–631;2011 2.Piacentino M, Pilleri M, Bartolomei L.Hardware-related infections after deep brain stimulation surgery: review of incidence, severity and management in 212 single-center procedures in the first year after implantation. Acta Neurochir (Wien) 153: 2337–2341;2011 3.Deep brain stimulation hardware-related infections: 10-year experience at a single institution. Abode-Iyamah KO, Chiang HY, Woodroffe RW, et al. J Neurosurg. 2018 Mar 1:1-10. doi: 10.3171/2017.9.JNS1780.

To cite this abstract in AMA style:

F. Yuzbasi, H. Kaptan. Treatment approaches for infection following DBS [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/treatment-approaches-for-infection-following-dbs/. Accessed June 14, 2025.
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