Objective: In this study, we describe the utilization of newly available visualization software for use as a deep brain stimulation (DBS) planning tool during the initial programming of patients with Parkinson’s disease (PD).

Background: Typically, optimization of deep brain stimulation (DBS) programming consists of a trial-and-error process involving the appraisal of various stimulation parameters in which both clinician assessment and subject reporting of clinical benefit are required. For many patients, this can be an inefficient and lengthy undertaking. The use of a visualization tool that can illustrate the location of the DBS lead in the patient’s own-segmented anatomy may help improve the efficiency of achieving programming optimization and outcomes specific to the individual patient within the initial as well as follow-up programming sessions.

Method: Data for this evaluation are being collected as part of the ongoing Vercise DBS Registry (ClinicalTrials.gov Identifier: NCT02071134), a prospective, on-label, multi-center, international registry in which participants are followed up out to 3-years post-implantation and assessed for their overall improvement in quality of life and PD motor symptoms. The Vercise DBS system (Boston Scientific) is a multiple-source, constant-rechargeable system. The visualization software (GUIDE XT, Boston Scientific) will be used during initial patient programming and data related to the duration of programming and efficacy/side-effect thresholds will be collected.

Results: Data collection and analysis are currently still ongoing. The overall time spent at initial programming will be reported and compared with standard-of-care.

Conclusion: Improving the overall experience of DBS in PD patients involves, at least in part, enhancing the ability to customize stimulation to address any inherent anatomical and physiological variability present within the population. Use of a visualization tool to help guide DBS programming, may offer the opportunity to improve how patients are programmed and thereby potentially contribute to achieving highly effective and desired clinical outcomes.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/utilization-of-new-visualization-software-for-deep-brain-stimulation-programming-using-a-multiple-source-constant-rechargeable-system/