Functional connectivity underpinnings of fatigue in “drug-naïve” patients with Parkinson’s disease
Objective: Using resting-state functional MRI, we investigated the functional correlates of fatigue in a cohort of “drug-naïve”patients with PD. Background: Fatigue is a common problem…Prevalence of impulse control disorders among adult Filipino patients with idiopathic Parkinson’s disease seen at a tertiary center in Manila
Objective: (1) To determine the prevalence and severity of Impulse Control Disorders (ICDs) in adult Filipino patients with idiopathic Parkinson's disease seen at a tertiary…“Words untold”
Objective: To highlight the salient clinical and pathologic features of primary progressive apraxia of speech through a clinical case presentation. Background: Apraxia of speech is…Dopamine reduces Parkinson’s tremor through increased thalamic inhibition
Objective: To identify cerebral mechanisms explaining the effects of dopamine on rest tremor in Parkinson's disease. Background: Resting tremor in Parkinson's disease is related to…Visual vs. automated analysis of [123I]FP-CIT SPECT scans in patients with parkinsonism
Objective: To investigate the differences between visual and automated analyses of brain dopamine transporter (DAT) SPECT scans. Background: Clinical evaluation of DAT SPECT scans typically…Effectiveness of Levodopa responsiveness of Blink reflex recovery: An objective method to differentiate Parkinsonian syndromes
Objective: We attempted to find an objective tool by assessing the variability of levodopa induced change in the blink reflex recovery to differentiate Parkinsonian syndromes.…The effect of dopaminergic therapy on stimulus-response learning and decision-making in Parkinson’s disease using fMRI
Objective: Our aim was to examine the neural correlates of stimulus-response (SR) learning in patients with Parkinson's disease (PD) on and off dopaminergic (DA) therapy…Modulation of local field potentials during gait in the STN of patients with Parkinson’s disease
Objective: PD patients with implanted DBS electrodes allow for the investigation of basal ganglia activity during gait. Background: Whereas the overall spectral content of local…The feasibility of measuring fatigability in early-stage Parkinson’s disease using functional MRI
Objective: To investigate the effect of fatiguability on brain activation in people with Parkinson's (PwP) in comparison with healthy volunteers(HV). Background: Fatiguability, an objective decline…Alterations in muscle synergies in early stage Parkinson’s disease
Objective: Identify whether muscle synergies are altered in stage I Parkinson's disease (PD). Background: Muscle synergies have been proposed as a mechanism utilized by the…
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