MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Evaluation of regional changes in striatal DAT binding in a progressing Parkinson’s disease (PD) cohort: Lessons for imaging biomarker assessment in disease-modifying therapeutic trials

    J.P. Seibyl, D. Jennings, K. Marek (New Haven, CT, USA)

    Objective: To evaluate subregion-dependent striatal changes in dopamine transporter (DAT) binding using 123-I Ioflupane SPECT in PD participants in the Parkinson Progression Marker Initiative (PPMI)…
  • 2016 International Congress

    Changes in serum amino acid levels with progression of Parkinson’s disease

    M. Figura, K. Kusmierska, E. Bucior, S. Szlufik, D. Koziorowski, Z. Jamrozik, A. Friedman, P. Janik (Warsaw, Poland)

    Objective: The purpose of this study was to analyze changes in serum amino acid profile with progression of Parkinson's disease (PD). Background: PD is a…
  • 2016 International Congress

    Pharmacokinetic-pharmacodynamic effects of apomorphine sublingual film (APL-130277) for the rapid management of OFF episodes in patients with Parkinson’s disease

    E.J. Pappert, B. Dzyngel, T. Bilbault, A. Agro (Toronto, ON, Canada)

    Objective: Determine the pharmacokinetic/pharmacodynamic effects of APL-130277 on OFF episodes in patients with Parkinson's disease (PD). Background: APL-130277 is a sublingual film being studied in…
  • 2016 International Congress

    DJ-1 regulates intracellular signaling in a highly cell type specific manner

    F. Giesert, D.M. Vogt Weisenhorn, U. Hafen, A. Romanov, A. Kurz-Drexler, W. Wurst (Neuherberg, Germany)

    Objective: To evaluate a cell type specific action of DJ-1, a PD and cancer associated gene, in intracellular signaling pathways. Background: Understanding the pathophysiology of…
  • 2016 International Congress

    Association of Parkinson’s disease severity and cortical and subcortical cognitive markers

    H. Duran-Meza, A.D. Santana-Vargas, J.D. Ramirez-Diossa, G.H. Terrazas Gonzalez, G. Millan-Rosas, U. Jimenez-Correa, M. Lopez-Ruiz (Mexico City, Mexico)

    Objective: To assess cortical and subcortical dysfunction in several stages of Parkinson's disease (PD) using the Parkinson's disease-cognitive rating scale (PD-CRS). Background: Cognitive impairment in…
  • 2016 International Congress

    Manganese-induced parkinsonism and motor neuron damage- Can there be a relationship?

    I. Giorgishvili, N. Lobjanidze, N. Akiashvili, M. Janelidze, M. Beridze (Tbilisi, Georgia)

    Objective: The aim of the study was evaluation of clinical, radiological and ENMG characteristic of ephedronic encephalopathy(EE). Background: The ephedrone abuse is widely spread among…
  • 2016 International Congress

    Fahr’s syndrome in a Filipino female with hearing loss and polycystic ovaries: A case report

    P.D. Dadgardoust, R.L. Rosales (Manila, Philippines)

    Objective: The objective of this case report is to document a case of Fahr's syndrome including its varied clinical manifestations. Background: Idiopathic basal ganglia calcification,…
  • 2016 International Congress

    A peripheral pathway to restless legs syndrome? Clues from familial amyloid polyneuropathy

    T. Teodoro, P. Viana, D. Abreu, I. Conceição, R. Peralta, J.J. Ferreira (Lisboa, Portugal)

    Objective: To investigated if RLS is increased in familial amyloid polyneuropathy related to transthyretin (TTR-FAP) and to identify factors associated with RLS in this population.…
  • 2016 International Congress

    SPAsticity in PractiCE (SPACE) – An international, observational study of botulinum toxin type A in spasticity

    J. Wissel, J. Harriss, O. Simon, K. Sternberg, N. Roche, C. Cantú-Brito, S. Khatkova, P. Säterö (Berlin, Germany)

    Objective: To collect real-world routine clinical practice data on effectiveness, safety, and quality of life (QoL) for botulinum toxin type A (BoNT-A) treatment of focal…
  • 2016 International Congress

    Long-term responsive deep brain stimulation in Tourette syndrome

    R.A. Molina, J.B. Shute, P.J. Rossi, E. Opri, K.D. Foote, M.S. Okun, A. Gunduz (Gainesville, FL, USA)

    Objective: To develop and measure the effectiveness of responsive deep brain stimulation for the treatment of Tourette syndrome. Background: Tourette's Syndrome (TS) is a paroxysmal…
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