Impact of white matter hyperintensity on motor compensation in Parkinson’s disease
Objective: To investigate the potential impact of white matter hyperintensity (WMH) on motor compensation in Parkinson's disease (PD). Background: WMHs, the loss of vascular integrity,…The efficacy of quantitative 99mTc-TRODAT-1 SPECT in diagnosis of aged patients with Parkinson’s disease
Objective: We aim to establish the normal reference with quantitative 99mTc-Trodat-1 (TRODAT) SPECT and verify the diagnostic performance in aged Parkinson's disease (PD) patients. Background:…Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson’s disease – Validation of novel fine motor functional effects
Objective: Targeted over-expression of human α-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates has been reported to lead…Spectral analysis of rapid eye movement (REM) sleep as a potential marker of neurodegenerative disease in REM sleep behavior disorder
Objective: To investigate whether spectral analysis at baseline in rapid eye movement (REM) sleep can differentiate patients with REM sleep behavior disorder (RBD) who will…Cognitive development in individuals with mild Parkinsonian signs
Objective: With this study we aimed to prospectively evaluate the development of cognitive performance in individuals with persistent Mild Parkinsonian Signs (MPS) compared to neurologically…Utility of the Montreal cognitive assessment for screening of mild cognitive impairment and dementia associated with Parkinson’s disease in a Colombian hospital
Objective: To determine the discriminant ability of the Montreal Cognitive Assessment (MOCA) for detection of dementia or any cognitive impairment in patients with Parkinson's disease…Impact of behavioral side effects on the management of Parkinson patients treated with dopamine agonists
Objective: To evaluate the clinician response to Parkinson patients who developed behavioral side effects from dopamine agonists. Background: Side effects from dopamine agonists can be…Cytokines in CSF and plasma as potential biomarkers for PD cognitive impairment
Objective: To assess CSF and plasmatic levels of cytokines as potential biomarkers of PD and PD mild cognitive impairment (PD-MCI). Background: Neuroinflammation may play a…Executive function and verbal fluency in patients with Parkinson’s disease
Objective: To determine whether the phonemic verbal fluency test is a purely cognitive measure or involves cognitive-motor interaction, if related to TMT. Background: Two of…Association between cognitive status and mobility performance in dual task condition in patients with Parkinson’s disease
Objective: To analyzed the association of cognitive status (CS) and mobility performance in dual task conditions in Parkinson's disease patients (PDP) and to assess the…
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