Specific in-patient’s rehabilitation improves postural and gait instability in Huntington’s disease
Objective: To evaluate long-term effects of targeted rehabilitation on postural and gait stability in the early and middle stages of Huntington disease (HD). Background: HD…Assessment of subclinical cerebellar involvement in progressive supranuclear palsy using SUIT based volumetric analysis
Objective: To explore the pattern of cerebellar atrophy if any, in patients with Progressive Supranuclear Palsy (PSP) using the SUIT (Spatially Unbiased atlas template for…Hemifacial spasm: Objective computation of vertebrobasilar vascular sinuosity
Objective: To objectively compute the degree of vascular sinuosity in the vertebrobasilar arteries in hemifacial spasm (HFS) and control subjects using a case-control MRI/A approach.…TMS-EEG markers of inhibitory deficits in Huntington’s disease
Objective: Given the GABAergic nature of TMS-evoked EEG activity, we tested whether GABAergic deficits in Huntington's disease (HD) patients produce any significant change in TMS-EEG…A cognitive fMRI study of non-manifesting LRRK2 and GBA carriers
Objective: To assess the cognitive profile of non-manifesting carriers of GBA and LRRK2 mutations using two fMRI tasks: a Stroop interference and N-Back working memory…Does cognitive decline contribute to poorer quality of life in incident Parkinson’s disease? A three year follow up
Objective: To investigate the impact of cognition and cognitive decline on quality of life (QoL) in an incident Parkinson's disease (PD) cohort over three years.…The practicalities of freezing of gait assessment methods
Objective: To highlight the available assessment tools and to provide practical, experience-based recommendations for reliable assessment of freezing of gait (FOG). Background: FOG is a…Real world conversion of levodopa to a novel extended release levodopa preparation: Determining predictors and dose ratios
Objective: To determine predictors of response and conversion ratios for a novel extended release levodopa preparation. Background: A new extended release levodopa preparation, Rytary®, has…Altered resting-state functional interhemispheric connectivity in Parkinson’s disease
Objective: To examine direct interhemispheric functional connectivity (FCi) in Parkinson's disease (PD) during resting-state fMRI and to investigate the relations between observed connectivity changes and…The role of striatal dopaminergic terminals in early de novo PD patients with speech impairment
Objective: To assess the role of striatal dopaminergic terminals in early de novo (untreated) Parkinson's disease (PD) patients with impairment of speech. Background: Dopamine has…
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