Mov Disord Vol 31, Suppl 2 Archives - Page 140 of 207 - MDS Abstracts

2016 International Congress
Oligomeric alpha-synuclein and glucocerebrosidase activity levels in GBA-associated Parkinson’s disease
A.K. Emelyanov, G.V. Baydakova, P.A. Andoskin, M.A. Nikolaev, K.A. Senkevich, I.V. Milyukhina, A.F. Yakimovskii, A.A. Timofeeva, E.Y. Fedotova, E.P. Nuzhnyi, S.N. Illarioshkin, E.Y. Zakharova, S.N. Pchelina (Saint-Petersburg, Russia)
Objective: To evaluate alterations in the phosphorylated, oligomeric alpha-synuclein and GBA activity levels in plasma from patients with sporadic Parkinson's disease (sPD), PD patients with…
2016 International Congress
Interest in genetic testing in Parkinson’s disease patients with deep brain stimulation
G. Pal, E. Tam, R. Bhavsar, C. Timms, L. Verhagen, D. Hall, K. Marder (Chicago, IL, USA)
Objective: To determine interest in genetic testing in Parkinson's disease (PD) patients with deep brain stimulation (DBS). Background: Approximately 27% of early-onset PD patients with…
2016 International Congress
Clinical profile of Wilson’s disease at Yangon General Hospital, Myanmar
S.M.M. Aye, K.M.P.P. Kyaw, Z. Myint Shwe, O. Ohnmar, Y.M. Aye, W.M. Thit (Yangon, Myanmar)
Objective: To evaluate clinical, biochemical and imaging profile of patients with Wilson's Disease (WD). Background: There was no reported case series of WD in Myanmar.This…
2016 International Congress
Clinical and neuroimaging outcomes up to 18 years after fetal tissue transplant for Parkinson’s disease
C. Henchcliffe, J. Carter, A. Hanineva, Y. Kang, J. Babich, S.M. Gollomp, A.P. Strafella, A. Fasano, L.D. Ravdin, N. Hellmers, C. McRae (New York, NY, USA)
Objective: To characterize clinical and radiological outcomes in 4 patients with Parkinson's disease (PD) at 16-18 years post-transplant of fetal ventral mesencephalic (fVM) tissue into…
2016 International Congress
PINK1-dependent clearance of depolarized mitochondria is driven by the UPS and can occur independently of (macro)autophagy
A. Rakovic, J. Ziegler, C.U. Mårtensson, J. Prasuhn, K. Shurkewitsch, P. König, H.L. Paulson, C. Klein (Luebeck, Germany)
Objective: To disect the role of macroautophagy in PINK1-/Parkin-dependent removal of depolarized mitochondria. Background: The ubiquitin ligase Parkin and mitochondrial kinase PINK1 function together in…
2016 International Congress
Analysis of relationships between spinal deformity and walking ability in Parkinson’s disease patients
Y. Nakamura, Y. Machida, T. Hanawa, M. Kanai, K. Tajima, S. Asano (Satte, Japan)
Objective: To determine the impact on walking ability of spinal deformity and imbalance as distinct from movement disorder in Parkinson's disease (PD). Background: Despite a…
2016 International Congress
Selenotranscriptomic analyses identify signature selenoproteins in brain regions in a mouse model of Parkinson’s disease
J.Y. Wang, X. Zhang, Y.L. Ye, H.H. Fan, H.M. Wu, W.H. Cheng, J.H. Zhu (Wenzhou, People's Republic of China)
Objective: In this study, we investigated the selenotranscriptome (24 selenoproteins in total) in five brain regions (cerebellum, substantia nigra, cortex, pons and hippocampus) in a…
2016 International Congress
Dysregulated macroautophagy and mitochondrial dynamics in PD with glucocerebrosidase mutations
S.H. Kuo, H. Li, A. Ham, M.M. Cheng, Y. Quan, D. Sulzer, G. Tang (New York, NY, USA)
Objective: To investigate markers of macroautophagy and mitochondrial dynamics in fibroblasts and postmortem brain of Parkinson's disease (PD) patients with glucoerebrosidase (GBA1) mutations and controls.…
2016 International Congress
Bcr-Abl tyrosine-kinase inhibitors (B-ATKI) and Parkinson’s disease (PD)
E.A. Shamim, S.F. Baker, F.F. Liu, K.K. Mane, J.G. Layug, S. Vupputuri, C.C. DiStasio, S.M. Khandhar, C. Neff, S. Van Den Eeden, C. Lungu, R. Cooley, H.S. Martel, C. Chen, J. Dorman, M.A. Sinkiewicz, J. Klingman (Largo, MD, USA)
Objective: Looking through the Kaiser Permanente National Parkinson's disease Registry, generated through the electronic medical records (EMR), we took a first step in looking at…
2016 International Congress
Reach-to-grasp impairments of both hands in individuals with Parkinson’s disease
S. Khacharoen, J. Tretriluxana, A. Pisarnpong, P. Chaiyawat (Nakhon Pathom, Thailand)
Objective: To compare the reach-to-grasp (RTG) planning, kinematics and coordination of the less- (left) and more affected (right) hand in Individuals with Parkinson's disease (PD)…