Mov Disord Vol 31, Suppl 2 Archives - Page 147 of 207 - MDS Abstracts

2016 International Congress
Ninjurin 1 gene D110a single nucleotide polymorphism as a genetic marker for nerve damage leprosy patients from South India
A. Sundaramoorthy, S. Keshavarao, A. Valsala Gopalakrishnan (Coimbatore, India)
Objective: Analyze the Ninjurin 1 gene single nucleotide polymorphisms in leprosy patients from south India, and the role of the gene in the nerve damage.…
2016 International Congress
Correlation among DNA methylation status and LINE-1 expression in rat brain
S. Mukherjee, K. Upadhyaya, D. Sharma (New Delhi, India)
Objective: Our objectives were to study the transcriptional expression of L1Rn elements in different brain regions and correlate with corresponding DNA methylation levels. Methods: Real…
2016 International Congress
Inflammatory profile discriminates clinical subtypes in LRRK2-associated PD
K. Brockmann, C. Schulte, N. Schneiderhan-Marra, A. Apel, C. Pont-Sunyer, D. Vilas, J. Ruiz-Martinez, M. Langkamp, J.C. Corvol, F. Cormier, T. Knorpp, T.O. Joos, A. Bernhard, T. Gasser, C. Marras, B. Schüle, J.O. Aasly, T. Foroud, J.F. Marti-Masso, A. Brice, E. Tolosa, D. Berg, W. Maetzler (Tübingen, Germany)
Objective: To evaluate whether inflammatory processes in PD patients with mutations in the LRRK2 gene (PD-LRRK2) are associated with modification of clinical features and disease…
2016 International Congress
Elevated SNCA expression in CD45+ peripheral blood cells in patients with dementia with Lewy bodies
N. Nikolaev, B. Lu.A., P.A. Andoskin, A. Emelyanov, A.E. Kopytova, K.A. Senkevich, I.V. Milyukhina, S.N. Pchelina (Saint-Petersburg, Russia)
Objective: To examine SNCA mRNA levels in CD45+ peripheral blood cells in patients with dementia with Lewy bodies (DLB), Parkinson's disease (PD) and individuals without…
2016 International Congress
Vitamin D receptor polymorphisms and Parkinson’s disease in a Korean population: Revisited
W. Jang, J.S. Kim (Gangneung, Korea)
Objective: We evaluated an association between PD and VDR polymorphisms including BsmI, FokI, ApaI, and TaqI and we also investigated the relationship between VDR polymorphisms…
2016 International Congress
SMPD1 mutations, acid-sphingomyelinase activity and α-synuclein accumulation in Parkinson’s disease
Z. Gan-Or, V. Mallett, O. Tavassoly, Y. Dauvilliers, C. Leblond, A. Ambalavanan, S. Laurent, S. Strong, D. Spiegelman, A. Dionne-Laporte, C. Liong, O. Levy, S. Fahn, C. Waters, P. Mazzoni, S. Kuo, W. Chung, B. Ford, K. Marder, U. Kang, P. Wolf, P. Oliva, X. Zhang, L. Clark, P. Dion, E. Fon, N. Dupre, G. Rouleau, R. Alcalay (Montreal, Canada)
Objective: To study the effects of SMPD1 (sphingomyelin phosphodiesterase-1 gene) variants and acid-sphingomyelinase (ASMase) activity on Parkinson's disease (PD), and the effect of SMPD1 knockdown…
2016 International Congress
The French experience of liver transplantation for severe neurological forms of Wilson disease
A. Poujois, R. Sobesky, W. Meissner, E. de Medeiros, C. Vanlemmens, A.S. Brunet, E. Broussolle, J.C. Duclos-Vallée, F. Woimant (Paris, France)
Objective: To evaluate the efficacy of liver transplantation (LT) in patients with severe neurological forms of Wilson disease (WD) who got clinically worse despite a…
2016 International Congress
Unconventional chaperone inhibits alpha-synuclein amyloid formation by promoting off-pathway aggregation
J. Bieschke, E. Illes-Toth, M. Shah, N. Wu, S. Verzini, P. Selenko, E. Wanker (Saint Louis, MO, USA)
Objective: To find new potential druggable targets that prevent alpha-synuclein aggregation and toxicity in Parkinson's disease. Background: Alpha-synuclein (aS) is the primary protein deposited in…
2016 International Congress
Alpha-synuclein gene variants may predict neurostimulation outcome
D. Weiss, S. Herrmann, L. Wang, C. Schulte, K. Brockmann, C. Plewnia, T. Gasser, M. Sharma, A. Gharabaghi, R. Krüger (Tübingen, Germany)
Objective: We aim to predict both treatment efficacy and disease progression in PD patients with subthalamic nucleus deep brain stimulation therapy (STN-DBS) by genotyping of…
2016 International Congress
Impairments in trunk muscle function influence head and trunk stability during walking in Parkinson’s disease fallers
M.H. Cole, G.A. Naughton, P.A. Silburn (Virginia, Australia)
Objective: This prospective study aimed to evaluate the relationship between impaired trunk muscle function, segmental coordination and future falls in people with Parkinson's disease (PD).…