Switching double-blind opicapone, entacapone or placebo to open-label opicapone: Efficacy results of the 1-year extension of study BIPARK I
Objective: Evaluate the efficacy of opicapone (OPC) in Parkinson's disease (PD) patients with motor fluctuations enrolled in the 1-year extension of study BIPARK I. Background:…Speech and voice range profile in patients with Parkinson’s disease with deep brain stimulation: Preliminary data
Objective: To assess the use of Voice Range Profile(VRP) and Speech Range Profile(SRP) in the evaluation of patients with on and off Deep brain stimulation(DBS).…Evaluation of impulse control disorders in fluctuating Parkinson’s disease patients under opicapone treatment
Objective: Evaluate the impulse control disorders reported as adverse events in phase III studies with opicapone (OPC) in fluctuating Parkinson's disease patients. Background: Impulse control…Can treadmill training facilitate the dual-task gait in Parkinson’s disease?
Objective: Investigate the effects of a single session of treadmill gait training combined with cognitive tasks on dual-task gait in Parkinson's disease. Background: The loss…Randomised trial comparing dopamine agonist, MAOB inhibitor and COMT inhibitor as adjuvant therapy in later Parkinson’s disease (PD)
Objective: The PD MED trial aimed to determine which class of drug provides the best patient-rated quality of life (QoL) when used as adjuvant therapy…Differential clinical outcomes in unifocal vs. multifocal premotor rTMS for Parkinson’s disease: A randomized trial
Objective: To compare changes in clinical outcomes after weekly low-frequency (LF) repetitive transcranial magnetic stimulation (rTMS) sessions over one vs. two pre-motor cortex (preMC) areas…The application of mobile health technology to increase physical activity in persons with Parkinson’s disease
Objective: To investigate the safety, acceptability and preliminary evidence of efficacy of a mobile health (mhealth) mediated home-based exercise program to increase physical activity in…Biseptol a new antiParkinsonian agent?
Objective: To evaluate the possible effect of combined intake of levodopa/carbidopa and trimethoprim/sulfamethoxazole on the duration of ON/OFF periods in a PD patient. Background: Drug…When is the worst period of nocturnal hypokinesia in Parkinson’s disease? A sensor-based analysis
Objective: To quantify the number of turning in bed throughout the night as a determinant of the severity of nocturnal hypokinesia. Background: Nocturnal hypokinesia or…Levodopa, placebo and rotigotine change biomarker levels for oxidative stress
Objective: The objective was to investigate the influence of the D1 receptor agonists levodopa and rotigotine compared with placebo on homocysteine and cysteinyl-glycine in plasma…
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