Elemental profiles as biomarkers for diagnosis and disease progression of Parkinson’s disease
Objective: This study aims to analyse the elemental profiles in the cerebrospinal fluid (CSF) of patients with idiopathic Parkinson´s disease (PD) and age-matched control patients…Effectivity and safety of rotigotine transdermal patch on motor and cognitive dysfunctions in Parkinson’s disease with dementia and dementia with Lewy bodies
Objective: This study aimed to demonstrate effectivity and safety of rotigotine transdermal patch (RTP) on motor and cognitive dysfunctions in patients with Parkinson's disease with…Human-derived α-synuclein antibody BIIB054 binds pathologic forms of α-synuclein and attenuates transmission of α-synuclein in vitro and in vivo
Objective: To identify and characterize a human antibody against α-synuclein (α-syn) for the clinical development of an immunotherapy for Parkinson's disease (PD). Background: α-syn plays…Voice harmonic amplitude differences before and after LSVT LOUDTM in Parkinson’s disease
Objective: To evaluate voice harmonic amplitudes from acoustic spectra of speech produced by subjects with Parkinson's disease (PD) before and after voice treatment, in order…Minimizing levodopa titration period for Parkinson’s disease (PD)
Objective: Develop an optimization algorithm that individualizes the pharmacokinetics-pharmacodynamics (PKPD) infusion models of levodopa, to improve the efficacy of dose titration and reduce the number…Effect of over(exaggerated) articulation technique in voice and speech of individuals with Parkinson’s disease with deep brain stimulation
Objective: To investigate the immediate effect and after 15minutes(min) of over articulation technique in individuals with Deep Brain Stimulation(DBS). Background: Studies evaluating the immediate effects…Improving drug discovery using brain oscillations as biomarkers of Parkinson’s disease
Objective: The aim of this study was to assess the use of cortical oscillations as translational biomarkers for drug development for the motor symptoms of…The potential therapeutic effect of intranasal administration of stem cells in rotenone model of Parkinson’s disease in mice
Objective: In this study we assessed the potential beneficial effect of intranasal administration of mesenchymal stem cells (MSCs) to rotenone model of PD in C57bl/6…Utility of IgGs subtypes in hemolytic anemia prevention and treatment maintenance in patients treated with continous infusion of apomorphine
Objective: The objetive of our study is to assess the utility of the subtypes IgG direct Coombs test (DCT) in maintenance apomorphine treatment without risk…Expiratory muscle training for the impaired loudness of speech in Parkinson’s disease: An open-label study
Objective: To investigate the efficacy of EMT for the impaired loudness of speech in patients with PD, we conducted an open-label pilot trial of EMT.…
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