Motor rigidity selectively associates with impaired odor identification in Parkinson’s disease
Objective: To investigate the relationship between impairments of the cardinal motor symptoms and odor identification deficits in Parkinson's disease (PD). Background: Although hyposmia has been…Faithful SGCE imprinting in iPSC-derived cortical neurons: An endogenous model system of myoclonus-dystonia
Objective: To test the potential of induced pluripotent stem cell (iPSC)-derived cortical neurons from Myoclonus-dystonia (M-D) patients when studying specific epigenetic and brain-specific aspects of…Incidence of dynamic aphasia in progressive supranuclear palsy
Objective: To evaluate of Incidence of dynamic aphasia in Progressive supranuclear palsy. Background: Progressive supranuclear palsy (PSP) is an akinetic-rigid syndrome of unknown aetiology which…Dorsal simultanagnosia as a cortical sign in the tauopathy spectrum
Objective: Clinical characterization of a tauopathy spectrum patient. Background: In recent years phenotypic overlap has been demonstrated between patients with progressive supranuclear palsy (PSP) pathology…LRRK2, MAPT and HTRA2 mutations in the pedigree of familial neurodegenerative parkinsonism with cognitive deterioration spanning five generations in a genetically isolated population of south-eastern Moravia, Czech Republic
Objective: To obtain genetic information about the individuals with confirmed parkinsonism in an isolated rural region in south-eastern Moravia, Czech Republic. Background: An epidemiological study…Clinical and instrumental features of multiple system atrophy with laryngeal stridor
Objective: To evaluate clinical and instrumental different features in two case series of multiple system atrophy (MSA) patients with or without laryngeal stridor. Background: MSA…Greater incidence of depressive symptoms in atypical parkinsonism: Importance of early screening
Objective: To evaluate the incidence of depressive symptoms in Parkinsonian patients in a large cohort followed at a tertiary movement disorders center. Background: Despite relative…Cognition, vision and visuo-cognition in gait in Parkinson’s disease
Objective: This study examined the selective but overlapping roles of cognition and vision in gait in Parkinson's disease (PD). To address this we studied; 1)…Non-motor symptoms trajectory in Parkinson’s disease: Magnitude and importance of the change
Objective: To determine the magnitude and clinical relevance of the change of non-motor symptoms (NMS) in Parkinson's disease (PD) patients over a 2-year follow-up. Background:…Neuropsychiatric disturbances in Parkinson’s disease patients’ with chronic pain
Objective: The study objective was to assess the neuropsychiatric profile in Moldavian Parkinson's disease patients with chronic pain. Background: Psychological factors can influence both the…
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