Pseudodystonic upper limb secondary to thalamic lesions: Usefulness of ultrasound-guided botulinum toxin treatment
Objective: Case reports. Background: Although botulinum toxin is routinely used as first-line treatment for focal dystonias, little is known about its usefulness in the treatment…Dystonia, myoclonus, and tremor without epilepsy associated with a mutation in STXBP1
Objective: Describe a presentation of abnormal movements associated with a mutation in STXBP1. Background: STXBP1, or the syntaxin binding protein 1 gene, is involved in…The serum response factor SRF protect dopamine (DA) neurons in Parkinson’s disease partially by mediate autophagy through a beclin 1-dependent pathway
Objective: To investigate the level of serum response factor(SRF) in rotenone-induced Parkinson's disease(PD) model and PD patients, and explore the potential protective role and underlying…Creutzfeldt-Jakob disease presenting predominantly with movement disorder: A case report
Objective: To highlight that Creutzfeldt-Jakob Disease can present predominantly with movement disorder. Background: Creutzfeldt-jakob Disease (CJD) is a rapidly progressive spongioform degeneration of the brain…TNF compromises lysosome acidification and reduces α-synuclein degradation via autophagy in dopaminergic cells
Objective: To investigate the effect of TNF on α-synuclein degradation and to explore the potential role of autophagy-lysosome pathway involved in this processs. Background: In…Predictive validity of statistical models of Parkinson’s disease progression
Objective: To develop statistical models of Parkinson's disease (PD) progression based on a transversal assessment and to explore its predictive value in a three-year follow-up.…Fall status and stepping response: Individuals with PD are differently influenced by side-affected
Objective: To identify differences in compensatory stepping responses (CSR) between Parkinson's disease (PD) fallers and non-fallers in response to external perturbations. Specifically, to investigate if…Examining the clinical profile of nelotanserin, a novel agent in development for Lewy body dementia
Objective: To examine the clinical profile of nelotanserin, a novel agent in development for the treatment of Lewy body dementia. Background: Although not FDA-approved for…Dopaminergic medicines are alternative drugs for treatment of motor disorders in ischemic stroke
Objective: To study the possibility of using levodopa and amantadine for the treatment of motor disorders in ischemic stroke after taking the standard treatment. Background:…Effects of videogame step training on gait adaptability in people with Parkinson´s disease – A randomized controlled trial
Objective: To evaluate the effect of home-based interactive videogame step training on gait adaptability performance in people with Parkinson's disease (PD). Background: The ability to…
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