Dopamine reduces Parkinson’s tremor through increased thalamic inhibition
Objective: To identify cerebral mechanisms explaining the effects of dopamine on rest tremor in Parkinson's disease. Background: Resting tremor in Parkinson's disease is related to…Visual vs. automated analysis of [123I]FP-CIT SPECT scans in patients with parkinsonism
Objective: To investigate the differences between visual and automated analyses of brain dopamine transporter (DAT) SPECT scans. Background: Clinical evaluation of DAT SPECT scans typically…Effectiveness of Levodopa responsiveness of Blink reflex recovery: An objective method to differentiate Parkinsonian syndromes
Objective: We attempted to find an objective tool by assessing the variability of levodopa induced change in the blink reflex recovery to differentiate Parkinsonian syndromes.…The effect of dopaminergic therapy on stimulus-response learning and decision-making in Parkinson’s disease using fMRI
Objective: Our aim was to examine the neural correlates of stimulus-response (SR) learning in patients with Parkinson's disease (PD) on and off dopaminergic (DA) therapy…Modulation of local field potentials during gait in the STN of patients with Parkinson’s disease
Objective: PD patients with implanted DBS electrodes allow for the investigation of basal ganglia activity during gait. Background: Whereas the overall spectral content of local…The feasibility of measuring fatigability in early-stage Parkinson’s disease using functional MRI
Objective: To investigate the effect of fatiguability on brain activation in people with Parkinson's (PwP) in comparison with healthy volunteers(HV). Background: Fatiguability, an objective decline…Alterations in muscle synergies in early stage Parkinson’s disease
Objective: Identify whether muscle synergies are altered in stage I Parkinson's disease (PD). Background: Muscle synergies have been proposed as a mechanism utilized by the…The patterns of olfactory function in Parksinson’s disease patients with mild cognitive impairment
Objective: To examine relationship between olfactory dysfunction and PD-MCI, and investigated the patterns of olfactory function in subtypes of PD-MCI patients using the Korean version…Levodopa impairs learning in healthy young adults: Implications for Parkinson’s disease
Objective: The objective was to investigate the effect of dopaminergic therapy on healthy young adults to test the dopamine overdose hypothesis. Background: Dopaminergic therapy improves…Association or causation? Orthostatic hypotension and cognitive impairment in α-synucleinopathies: A systematic review
Objective: To systematically review the literature for evidence of an association between orthostatic hypotension (OH) and cognitive impairment (CI) in α-synucleinopathies and to discuss possible…
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