Age associated effects of levodopa administration on striatal acetylcholinesterase activity
Objective: The aim of this study was to compare short- and long-term effects of levodopa on acetylcholinesterase activity in young and old rat brain striatum.…Beyond initial clinical phenotype of Madelung disease: Myoclonus, gait disorder and multisystem involvement led to genetic diagnosis
Objective: To report the clinical phenotype of an uncommon hereditary systemic disease with slowly progressive gait and movement disorder with genetic identification of two concurrent…Persistent myoclonic dystonia due to SCL2A1 mutation
Objective: We present a young woman with myoclonic dystonia due to a novel mutation in SCL2A1 gene. Background: Mutations in the SCL2A1 gene can cause…Safety and efficacy of escalating doses of incobotulinumtoxinA (400-800U): Increasing improvements in disability due to multifocal upper- and lower-limb spasticity
Objective: To assess the safety and efficacy of escalating incobotulinumtoxinA doses (400-800U) in patients with spasticity. Background: Botulinum toxin treatment at higher doses than currently…Do different tic phenotypes have different responses to comprehensive behavioral intervention for tics (CBIT)?
Objective: To evaluate 1) the types of tics undergoing CBIT at an expert movement disorders center and 2) to evaluate the response of each tic…Altered connectivity within the cerebello-thalamo-cortical network in essential tremor: A resting state fMRI study
Objective: To evaluate the tremor network in Essential Tremor(ET) patients in rest conditions with respect to Healthy Controls(HC). Background: Pathophysiology of ET is poorly understood.…Isolated finger tremor in Parkinson’s disease and essential tremor
Objective: To establish whether isolated hand fingers tremor (IFT) is more frequent in Pakinson's (PD) disease than in essential tremor (ET). Background: Postural tremor may…Quantitative assessment of DBS-induced gait disorder in patients with essential tremor
Objective: To investigate changes in gait coordination quantitatively in patients with essential tremor (ET) under chronic bilateral high-frequency stimulation of the nucleus ventralis intermedius (VIM).…Sub-acute rapidly progressive cerebellar ataxia – A case of JC virus associated granule cell neuronopathy (GCN)
Objective: To describe a case of JC virus associated GCN. Background: JC virus associated CNS disease most commonly presents as progressive multifocal leukoencephalopathy. A less…Psychogenic movement disorder in cerebellar atrophy
Objective: Description of a patient with psychogenic movement disorder showing cerebellar atrophy in neuroimaging. Background: Psychogenic movement disorders are typically characterized by abnormal involuntary movements…
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