Increased anti-MAG autoantibodies titers in Parkinson’s disease
Objective: To search for biomarkers of neurodegenerative process in Parkinson's disease (PD).There is emerging evidence that humoral response may be involved in the pathogenesis and…Astroglia exert a neuro-protective role in Parkinson’s disease by reducing oxygen stress through dopamine-induced activation of the pentose-phosphate pathway
Objective: Although dopaminergic neurons themselves take up most of the released dopamine (DA), a part of the DA appears to be taken up by astroglia.…Increased energy expenditure in early Parkinson’s disease during exercise
Objective: To measure both resting energy expenditure rate (REER) and energy expenditure during mild to moderate exercise in patients with early Parkinson's disease (PD) that…Is the assessment of 5 meters of gait with body-worn-sensors enough to recognize Parkinsonian gait?
Objective: To classify step-by-step gait patterns of Parkinson's disease (PD) patients and older adults from the assessment of short episodes of gait with body-worn-sensors (BFS)…Lymphocytes have a detrimental effect on motor behavior in the AAV1/2 A53T α-synuclein mouse model of Parkinson’s disease
Objective: To determine the contribution of the adaptive immune system in the pathogenesis of a mouse model of Parkinson's disease (PD) based on AAV1/2 driven…Dynamic and static posturographic analysis among fallers and non- faller Parkinson’s disease (PD) patients using Neurocom SMART EquiTest
Objective: The purpose of this investigation is to study both the sensory and motor aspects of voluntary and automatic postural control using static and dynamic…Mild mitochondrial impairment promotes corticostriatal synaptic plasticity alterations in PINK1 heterozygous knockout mice
Objective: To investigate the effects of the exposure to low-dose rotenone of heterozygous PINK1 knockout (PINK1+/-) mice, compared to their wild-type littermates (PINK1+/+), on dopamine-dependent…Sodium butyrate attenuates rotenone-induced neurodegeneration via enhancing autophagy and preventing α-synuclein aggregation
Objective: To investigate whether sodium butyrate (NaB) could enhance autophagy and thus exert a neuroprotective effect through the modulation of α-synuclein in animal models of…Molecular landscape of Parkinson’s disease reveals a key role for lipids and lipoproteins
Objective: Integrate available genetic and expression data to generate a molecular landscape of Parkinson's disease (PD) in order to identify key disease mechanisms that may…Cortical role in the freezing of gait in Parkinson’s disease
Objective: In this study, we aimed to investigate the neural underpinning of freezing of gait (FOG) in Parkinson's disease (PD), especially the role of the…
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