AntiParkinsonian treatment patterns and motor complications among patients with Parkinson´s disease in Estonia
Objective: To evaluate pharmacological treatment patterns in patients with Parkinson´s disease (PD), prevalence of motor complications, and factors associated with them. Background: Levodopa is the…Progress in the development of small molecules based on the coumarin core as multifunctional neuroprotective agents
Objective: Taking into account the background of our research group and the knowledge that MAO and ChE activity generates ROS that cause neuronal cell death,…Drug safety in the pharmacotherapy of Parkinson’s disease
Objective: Detection of the most common and most serious drug-related problems in the pharmacotherapy of Parkinson's disease (PD), particularly with focus on interactions and contraindications…Effect of pharmacist-led interventions on motor symptoms and quality of life in Parkinson’s patients: A pilot study
Objective: Improvement of on-off symptoms in ambulatory patients with Parkinson's disease (PD) by introduction of a multi-faceted medication optimization program. This consisted of a patient…Improvement of freezing of gait with intestinal levodopa infusion in advanced Parkinson’s disease patients
Objective: To determine whether levodopa-carbidopa intestinal gel (LCIG) infusion is able to improve freezing of gait (FOG) in advanced Parkinson's disease (PD) patients. Background: FOG…Use of nicotine gum to treat acute low blood pressure in Parkinson’s disease
Objective: To evaluate (1) how nicotine chewing gum is tolerated (2) how nicotine chewing gum affects acute low blood pressure (BP) in Parkinson's disease (PD).…A phase II, pragmatic, randomized clinical trial on a high-intensity exercise and fall prevention boot camp for Parkinson’s disease: Feasibility and safety
Objective: To test the feasibility and safety of a high-intensity exercise and fall prevention boot camp (HIBC) in people with Parkinson's disease (PD). Background: Most…VANTAGE trial: Three year outcomes of a prospective, multi-center trial evaluating deep brain stimulation with a new multiple-source, constant-current rechargeable system in Parkinson’s disease
Objective: The VANTAGE study assesses motor improvement in moderate-to-severe Parkinson's disease (PD) following bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) using a new, implantable,…Duodenal levodopa infusion: Safety and efficacy in a 6 years outpatient follow-up
Objective: To reduce the risk of adverse events and dropout rate in patients. Background: Duodenal levodopa infusion (DLI) is used for the treatment of advanced…Patient experiences following Parkinson’s disease treatment with inhaled levodopa: Results from a Phase 2b study
Objective: To report patient experiences from a clinical trial investigating Parkinson's disease (PD) control following treatment with inhaled levodopa. Background: CVT-301, an inhaled levodopa powder…
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