Loss of heart rate variability in ALS: Time and frequency domain assessment
Objective: The aim of this study was to investigate alterations in cardiac autonomic control during sleep in patients affected by ALS. Background: Amyotrophic lateral sclerosis…Relationship between balance, trunk impairment and hand function in Parkinson’s disease
Objective: Our aim is to examine the relationship between balance, trunk impairment and hand function in patients with PD. Background: Parkinson's disease (PD) is the…STRONG VOICE: Design of a multisite, open-label, longitudinal registry for patients with neurogenic dysphonia/dysphagia treated with vocal fold augmentation
Objective: To describe the benefits and risks of vocal fold augmentation treatment for patients with neurogenic dysphonia/dysphagia. Background: Neurogenic dysphonia/dysphagia represents laryngeal dysfunction, usually with…Neuroprotection effect of an endogenous amine, 1MeTIQ against disturbances in dopamine release induced by the neurotoxin, 6-OHDA: In vivo microdialysis study
Objective: The aim of the present study was to investigated using microdialysis methodology the impact of 1MeTIQ on the disturbances of in vivo dopamine release…A computational model of iron transport between the blood circulation and the brain
Objective: To create a mechanistic computational model of iron transport between the circulation and brain, permitting in silico investigation of homeostatic regulation of iron at…Dynamic prediction for multiple repeated measures and event time data: An application to Parkinson’s disease
Objective: To develop methods for model-based personalized dynamic prediction of future outcome measure trajectories and risks of target events for the Parkinson's disease patients. Background:…Duloxetine, a serotonin and norepinephrine reuptake inhibitor, reduces daily OFF time in Parkinson’s disease
Objective: To evaluate efficacy of duloxetine on motor symptoms in Parkinson's disease (PD) patients with wearing-off in an open label trial. Background: Duloxetine, a serotonin…Safety, pharmacokinetics, and efficacy of levodopa prodrug ONO-2160/CD: A study in patients with Parkinson’s disease
Objective: The objective of this study was to evaluate the safety, pharmacokinetic profile, and efficacy of ONO-2160/carbidopa (CD) and to compare them with an immediate-release…Exploring therapeutic viability of a non-dopaminergic target for Parkinson’s disease
Objective: Non-dopaminergic protein drug targets are of high interest to develop adjuvant treatments for currently insufficiently addressed symptoms of PD. RGS4, a regulator of G-protein…Effects of combined repetitive transcranial magnetic stimulation and treadmill training on gait performance in Parkinson’s disease
Objective: To evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) with treadmill training on walking performance and corticomotor excitability in people with Parkinson's disease…
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