Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington’s disease gene carriers
Objective: Using positron emission tomography (PET) with [11C]IMA107, we investigated the in vivo expression of PDE10A in extra-striatal regions in a cohort of 12 early…Verbatim patient-reported outcomes and trails making test B (TMT-B) performance in the REACH2HD trial
Objective: Examine the relationship between Trails Making Test B (TMT-B) performance and bothersome cognitive complaints among Huntington Disease (HD) research participants in the REACH2HD randomized-controlled…Maintenance of balance function in patients with HD treated with deutetrabenazine, as measured by Berg balance test (BBT) in First-HD
Objective: To assess the effect of deutetrabenazine treatment on balance using the BBT in patients with HD in First-HD. Background: Patients with HD have disrupted…A health cost analysis for Huntington disease in Peru
Objective: To estimate economic costs of caring for an individual with Huntington disease from the patients and caregivers perspective. Background: Huntington disease (HD) is a…99mTc-TRODAT-1 SPECT findings in a patient with sporadic Creutzfeldt-Jakob disease
Objective: To report a case of sporadic CJD presenting insomnia,vertigo, ataxia and parkinsonism as first symptoms and describes the 99mTc-TRODAT-1 SPECT findings. Background: CJD is…Movement execution but not preparation modulates somatosensory temporal discrimination thresholds in healthy subjects
Objective: The aim of the study was to investigate in healthy subjects whether somatosensory temporal discrimination threshold (STDT) is influenced by movement execution and preparation.…Disruption of functional connectivity in Parkinson’s disease patients presenting phonemic fluency impairment
Objective: This study was designed to clarify the changes of detailed functional connectivity in association with phonemic fluency deficits in Parkinson's disease (PD) patients using…Gray/white matter contrast loss correlates with clinical severity and visuospatial impairment in Parkinson’s disease patients
Objective: The aim of our study was to test if PD patients differ from healthy controls (HC) in GWR and if this MRI parameter has…Risk factors of wearing-off phenomenon in Parkinson’s disease in Japan
Objective: Parkinson's disease (PD) is one of common progressive neurodegenerative disorder involving nigrostriatal dopaminergic neurons. The aim of this study was to investigate risk factors…Diverse effects of alpha-synuclein fibrils on various neuron cell lines, using different buffers
Objective: To investigate the neurotoxic properties of alpha-synuclein (α-Syn) aggregation in different buffers including PBS, SBF and Tris on altered cell lines, SHSY5Y, SK-N-MC and…
- « Previous Page
- 1
- …
- 70
- 71
- 72
- 73
- 74
- …
- 207
- Next Page »