Movement related beta oscillatory activity during self-paced wrist movement in the human subthalamic nucleus
Objective: To explore voluntary movement related neuronal activity in the subthalamic nucleus in patients with Parkinson's disease (PD). Background: How the human basal ganglia processes…Inferring the coupling of motor related brain areas during paced finger tapping in Parkinson’s patients
Objective: To analyze the coupling and causal interplay of motor related brain areas in Parkinson's patients during the performance of externally and internally paced finger…Sensory and motor aspects of rhythmic entrainment in Parkinson’s disease
Objective: To evaluate entrainment of MEG-recorded brain oscillations induced by a rhythmic task structure in patients with Parkinson's disease (PD). Background: PD patients do not…Influence of different spike sorting algorithms on the detection of single unit spiking activity in the subthalamic nucleus of patients with Parkinson’s disease
Objective: To determine the most suitable spike sorting algorithm for intraoperatively recorded extracellular currents in the subthalamic nucleus (STN) of patients with Parkinson's disease (PD).…Dopamine and task-dependent evolution of oscillatory activity in the subthalamic nucleus (STN) and coupling between the STN local field potential and muscle activity in Parkinson’s disease
Objective: To investigate how subthalamic nucleus local field potentials (STN-LFP) and coupling between STN-LFP and electromyogram (EMG) in static and phasic movements are modulated by…Heart rate variability to differentiate dementia with Lewy bodies from Alzheimer’s disease in patients with mild cognitive impairment
Objective: We aimed to determine whether heart rate variability (HRV) can aid in the differentiation of DLB from AD at the MCI stage. Background: Mild…Modeling dementia with Lewy bodies using patient-derived neurons
Objective: To model Dementia with Lewy bodies (DLB) using neurons derived from patients clinically diagnosed with the disease. Background: A major challenge in neurodegenerative disease…Catechol-o-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson’s disease
Objective: The Catechol-O-Methyltransferase (COMT) Val158Met polymorphism has been proposed to be associated with increased risk of PD and have a specific impact on dopamine-mediated prefrontal…Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson’s disease
Objective: To investigate the role of APOE, MAPT, COMT, SNCA and GBA genes in both striatal dopaminergic denervation and the development of dementia in Parkinson's…Occurrence and pattern of cognitive deficits in prodromal Parkinson’s disease
Objective: To assess a possible cognitive impairment and its specific profile in the prodromal phase of Parkinson's disease (PD). Background: Cognitive impairment is common in…
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