ND0701: A novel safe concentrated apomorphine formulation for continuous subcutaneous administration via a patch pump
Objective: To characterize the local safety and PK of a novel apomorphine formulation, ND0701, in comparison to a commercially available apomorphine–HCl solution. Background: Apomorphine is…The Luxembourg Parkinson’s study: Integrating the Lewy body composite risk score into a longitudinal study
Objective: To validate the LBCRS in a longitudinal national cohort study. The Lewy Body Composite Risk ScorePlease rate the following physical findings being present or…Changes in handwriting following repetitive transcranial magnetic stimulation over pre-motor cortex in Parkinson’s disease
Objective: To observe changes in handwriting following administration of repetitive transcranial magnetic stimulation (rTMS) over pre-motor cortex (pre-MC) in patients with PD. Background: Patients with…Balance and gait disturbances in Parkinson’s disease patients with falls and freezing of gait
Objective: To assess balance and gait disturbances in Parkinson's disease (PD) patients with falls and freezing of gait (FOG). Background: Falls and freezing of gait…The impact of STN DBS on kinetic tremor in Parkinson’s disease patients
Objective: The aim of the study is to evaluate the impact of STN DBS on kinetic tremor in PD patients in comparison to pharmacologically treated…Botulinum toxin in cerebral palsy children with gait disorder: Different therapy approaches
Objective: The purpose of this work was to study the effectiveness of different therapy approaches with Botulinum toxin type A (BTX-A) in Cerebral Palsy (CP)…Sensor-based motor state detection in Parkinson’s disease to approach personalized therapy delivery
Objective: As primary objective, we acquire a data pool of medically-treated PD patients with motor fluctuations to determine the sensitivity and specificity of algorithms capable…RE-024: Mechanism of action and efficacy in non-clinical models
Objective: To confirm the mechanism of action of RE-024, and evaluate its activity in human cellular models and brain penetration in animal models. Background: Pantothenate…Effects of subthalamic deep brain stimulation in motor and nonmotor function in Parkinson’s disease patients with parkin mutation
Objective: The aim of our study was to evaluate prospectively the changes in motor, nonmotor symptoms (NMS) and quality of life produced by subthalamic deep…Toward clinical use of electrode localizations in deep brain stimulation therapy
Objective: To develop an open source software capable of performing electrode localizations certified for clinical use in deep brain stimulation therapy. Background: Deep brain stimulation…
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