MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Striatal PDE10 expression in Parkinson’s disease (PD) and healthy controls using [18F]MNI-659 PET imaging

    D.S. Russell, D.L. Jennings, O. Barret, G.D. Tamagnan, D. Alagille, J.P. Seibyl, K.L. Marek (New Haven, CT, USA)

    Objective: To evaluate the feasibility of [18F]MNI-659 PET, a striatal PDE10A imaging tracer, as a imaging biomarker in PD. Background: PDE10 is highly and specifically…
  • 2016 International Congress

    Longitudinal cerebrospinal fluid biomarkers in early Parkinson’s disease and healthy controls

    B. Mollenhauer, C.J. Caspell-Garcia, C.S. Coffey, P. Taylor, L.M. Shaw, J.Q. Trojanowski, A. Singleton, M. Frasier, K. Marek, D.R. Galasko (Kassel, Germany)

    Objective: To analyze changes in levels of four distinct biomarkers in drug-naïve Parkinson's disease (PD) subjects in cerebrospinal fluid (CSF) over 6- and 12 mo…
  • 2016 International Congress

    Valproate-associated parkinsonism – A critical review of the literature

    F. Brugger, K.P. Bhatia, F.M.C. Besag (St. Gallen, Switzerland)

    Objective: To provide a critical review of the existing literature on valproate-associated parkinsonism and to discuss possible mechanisms. Background: Valproate was first approved as an…
  • 2016 International Congress

    Transient myoclonic state in the elderly: A new entity in the classification of myoclonus

    T. Hashimoto, T. Doden, H. Sato (Matsumoto, Japan)

    Objective: To clarify the clinical picture of transient myoclonic state in elderly patients and to establish a position in the classification of myoclonus. Background: Transient…
  • 2016 International Congress

    Neurophysiological investigation of brainstem in idiopathic REM sleep behavior disorder (iRBD) through vestibular evoked myogenic potentials (VEMPs)

    E.R. de Natale, F. Ginatempo, I. Laccu, B. Mercante, A. Manca, M. Figorilli, M. Puligheddu, F. Deriu (Sassari, Italy)

    Objective: To investigate the degree of brainstem impairment in a cohort of patients with iRBD through recording of a VEMPs battery able to indirectly assess…
  • 2016 International Congress

    The temporal relationship between premonitory sensations and tics compared to obsessions

    V.C. Brandt, C. Beck, J. Hermanns, T. Bäumer, B. Zurowski, S. Anders, A. Münchau (Lübeck, Germany)

    Objective: Investigating the real-time relationship between premonitory urges and tics as compared to the urge to blink in healthy controls and the urge to execute…
  • 2016 International Congress

    Individualized botulinum toxin type A therapy of bilateral upper limb essential tremor by multi-sensor kinematic technology

    O. Samotus, H. Moradi, M. Jog (London, ON, Canada)

    Objective: To demonstrate efficacious and safe reduction in bilateral upper limb tremor severity by serial botulinum toxin type A injection parameters kinematically determined using a…
  • 2016 International Congress

    "Are patients with familial ET distinct from those with sporadic ET? Insight from 250 patients"

    M. Manjunath, A. Lenka, K. Jhunjhunwala, K.S. Bhalsing, P.K. Pal (Bengaluru, India)

    Objective: To explore if patients with familial ET(FET) are clinically and demographically distinct from those with sporadic ET(SET). Background: Essential tremor(ET) is the commonest tremor…
  • 2016 International Congress

    Timing control of gait in essential tremor patients vs. age-matched controls

    A.K. Rao, E.D. Louis, A.K. Rao (New York, NY, USA)

    Objective: (1) To examine if gait timing control is impaired in ET patients compared with age-matched controls. (2) To examine whether timing impairments are related…
  • 2016 International Congress

    Quantitative analysis of tremor in patients with cerebellar and brainstem lesions

    A. Kovács, Z. Farkas, A. Kamondi (Budapest, Hungary)

    Objective: The aim of our study was to investigate the characteristics of tremor in patients with cerebellar or brainstem lesions. Background: The cerebellum and the…
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