A Phase 2, Open-Label, Dose-Escalating Study to Evaluate the Safety and Preliminary Efficacy of Daxibotulinumtoxina for Injection (RT002) in Isolated Cervical Dystonia
Objective: To report preliminary 24-week outcomes of an open-label trial of daxibotulinumtoxinA for injection (RT002) for the treatment of isolated cervical dystonia (CD). (ClinicalTrials.gov ID: NCT02706795) Background:…Cost-utility analysis of flexible interval incobotulinumtoxinA versus onabotulinumtoxinA in the management of blepharospasm and cervical dystonia in Ontario, Canada.
Objective: To carry out a cost-utility analysis for IncoBTX administered with flexible treatment intervals compared to OnaBTX in the management of BL and CD from…Clinical effects are persistent at the end of one abobotulinumtoxinA injection cycle in cervical dystonia – results from a meta-analysis of 1091 subjects
Objective: Evaluate the impact of one injection cycle of abobotulinumtoxinA (AboBoNT-A; Dysport®) on the clinical characteristics of cervical dystonia (CD). Background: The pharmacologic effects of…Oromandibular dystonia (OMD): A Prospective, Single-Blind Trial of AbobotulinumtoxinA (AboA)
Objective: To examine the safety and efficacy of AboA in OMD Background: OMD causes involuntary movements of the lower facial, masticatory, and lingual muscles. The…Sensory trick in a dystonic patient: insights from Magnetoencephalogram
Objective: To explore the mechanism of action of a sensory trick by comparing cerebral oscillations at network level, with a sensory trick and administration of…Physical Activity in Early Parkinson Disease
Objective: To characterize physical activity habits in patients with early Parkinson disease (PD). Background: Physical activity is an important therapy for PD as it may…Oscillatory Activity in the Nucleus Basalis of Meynert
Objective: Characterize oscillatory activity in and around the nucleus basalis of Meynert (NBM). Background: The NBM is the major source of cholinergic innervation to the…Development of a Clinical Outcomes Assessment (COA) in Pantothenate-Kinase Associated Neurodegeneration (PKAN): Item Generation and Clinimetric Properties
Objective: To develop a clinical outcome assessment (COA) scale that measures key aspects of functioning and daily living in patients with pantothenate kinase-associated neurodegeneration (PKAN)…Gait asymmetry and asymmetry index in a sample of patients with PD and control group in Cali – Colombia.
Objective: To objectively evaluate gait asymmetry and asymmetry index as a measure of gait in a sample of patients with PD compared to a control…A single aerobic exercise session of treadmill increases BDNF levels in Parkinson’s disease patients
Objective: The aim of this study was to investigate the effect of a single session moderate-intensity treadmill exercise on serum levels brain-derived neurotrophic factor (BDNF)…
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