Inhibition of mitochondrial complex I synthesis by chloramphenicol mitigates dopaminergic neuronal cell loss in PQ-induced parkinsonism
Objective: To find the potent drug for prevention of PD, we screened with above 1000 drugs in the PQ treated cells which currently used drug…Salivary Alpha-Synuclein in Aging
Objective: We measured alpha-synuclein total (a-syntotal) and alpha-synuclein oligomers (a-synolig) concentration in 70 healthy subjects, of different ages (from 18 to 88 years old) to…Insulin Resistance In Non-Diabetic People With Parkinson’s Disease
Objective: To study the incidence of insulin resistance (IR) in people with Parkinson's Disease (PD) and its relationship with motor and non-motor symptoms of the…Perrault syndrome: CLPP-Knock-Out mouse brain shows accumulation of mitoribosomes
Objective: We aimed to document the alterations of pathways and molecules that underlie brain pathology in the Perrault syndrome. Background: Perrault syndrome is an autosomal…Familial Creutzfeldt-Jakob Disease with an E200K Mutation in Peru: A Case Report
Objective: To describe the clinical and molecular features of a familial Creutzfeldt-Jakob Disease (fCJD) case in Peru. Background: Creutzfeldt - Jakob disease (CJD) is characterized…Reliability of Continuous Parkinson’s Assessment Using Wearables
Objective: To evaluate test-retest reliability and determine the optimal number of days of use for wearable sensors and a mobile software app to continuously and…Instrumental Measurement of Stepping in Place – Detection of Asymmetry and Freezing of Gait
Objective: To detect freezing of gait (FoG) and quantify movement asymmetry from markerless full body motion capture with Microsoft Kinect™ during the execution of a…The influence of neurorehabilitation on Parkinson medication
Objective: To investigate the influence of neurorehabilitation on the dose changes of Parkinson medication over time. Background: In progressive disorders such as Parkinson’s disease (PD),…Determinant factors of treatment adherence in Parkinson’s disease
Objective: To determine factors predicting treatment adherence in patients with idiopathic Parkinson’s disease. Background: Parkinson’s disease is the second most common cause of neurodegenerative disease…Interaction of dietary protein with levodopa in Parkinson disease.
Objective: To study the effect of dietary protein on levodopa effectiveness in Parkinson disease (PD) patients. Background: Levodopa transport across the blood brain barrier is…
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