MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2017 International Congress

    Clinical utility of chronic directional subthalamic Deep Brain Stimulatoin in Parkinson’s Disease

    C. Hartmann, L. Venkatesan, P. Slotty, J. Vesper, A. Schnitzler (Düsseldorf, Germany)

    Objective: Here, we present our 3-month clinical experience with subthalamic directional DBS in treating Parkinson’s disease (PD) symptoms. Background: Directional Deep Brain Stimulation (DBS) is…
  • 2017 International Congress

    Twiddler Syndrome in Deep Brain Stimulation

    N. Durmaz Celik, M. Vural, S. Ozkan (Eskişehir, Turkey)

    Objective: Twiddler syndrome is one of the major complications in DBS treatment.    Background: The patient intentionally and subconsciously spins internal pulse generator Spinning generally causes…
  • 2017 International Congress

    Effect of Deutetrabenazine on Quality of Life in Patients With Tardive Dyskinesia in AIM-TD, a 12-Week Double-Blind, Placebo-Controlled Study

    S. Factor, K. Anderson, D. Stamler, M. Davis, R. Hauser, J. Isojärvi, L. Jarskog, J. Jimenez-Shahed, R. Kumar, S. Ochudlo, W. Ondo, H. Fernandez (Atlanta, GA, USA)

    Objective: To assess the effect of deutetrabenazine (DTB) on quality of life (QoL) of patients with tardive dyskinesia (TD) as measured by the modified Craniocervical…
  • 2017 International Congress

    D2 receptor mediated DARPP32/PP1α signaling is responsible for cadmium induced Parkinson’s like behavioral alterations in rats

    R. Gupta, R. Shukla, V. Khanna (Luckno, India)

    Objective: To identify the specificity of dopamine D2 receptor mediated signaling in cadmium mediated motor alterations Background: Cadmium, a heavy metal, is to known to…
  • 2017 International Congress

    Genetic and Clinical Analysis of Cerebral Calcifications

    V. Chelban, R. Kaiyrzhanov, H. Houlden (London, United Kingdom)

    Objective: Genetic and clinical analysis in primary cerebral calcification. Background: Cerebral calcification is associated with a variety of disorders of different aetiologies. To date, the primary…
  • 2017 International Congress

    Spastic paraplegia type 4: a novel SPAST splice site donor mutation and expansion of the phenotype variability

    A. Orlacchio, C. Montecchiani, R. Miyamoto, M. Mearini, L. D'Onofrio, M. Miele, F. Gaudiello, Y. Izumi, C. Caltagirone, R. Kaji, T. Kawarai (Rome, Italy)

    Objective: The aim of this study is to reveal molecular pathogenicity and genotype-phenotype correlations in spastic paraplegia type 4 (SPG4). Background: Mutations in SPG4/SPAST represent…
  • 2017 International Congress

    Juvenile Huntington Disease (JHD) subjects’ stratification according to the mutation-length

    M. Marano, M. Marano, S. Migliore, S. Maffi, F. Consoli, A. Ciammola, E. Gatto, F. Squitieri (Rome, Italy)

    Objective: To identify clinical and genetic markers to differ JHD from adult Huntington disease (HD) and to monitor JHD progression Background: JHD is a HD…
  • 2017 International Congress

    Dynamic prediction of motor diagnosis in Huntington’s disease using a joint modeling approach

    K. Li, E. Furr Stimming, S. Luo, K. Li (Houston, TX, USA)

    Objective: Compare various clinical and biomarker trajectories for tracking Huntington's disease (HD) progression and predicting motor conversion. Background: Huntington’s disease (HD) is a fatal neurodegenerative disease…
  • 2017 International Congress

    Synthesis and pharmacological evaluation of 16-aryldieno steroids as anti-parkinsonian agents in LPS induced Neuroinflammation Model of Rat

    R. Bansal, R. Singh (Chandigarh, India)

    Objective: The present study is aimed at design and synthesis of new therapeutically useful steroidal neuroprotective derivatives as anti-parkinsonian agents. The new 16-aryldieno steroidal derivatives…
  • 2017 International Congress

    Role of the subthalamic nucleus and globus pallidus internus in response inhibition during masked prime tasks in human

    A. Singh, I. Niazi, V. Sharma, K. Boetzel (Minneapolis, MN, USA)

    Objective: To study the subthalamic nucleus (STN) and globus pallidus internus (GPi) local filed potential (LFP) activities in the response inhibition during masked prime tasks…
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