Fentanyl Induced Chorea: A Case Report
Objective: To report the acute onset of generalized chorea as an adverse reaction to transdermal fentanyl Background: Chorea can present with degenerative conditions or in an…Cholinergic activity, mobility, and attention in mild cognitive impairment
Objective: The aim of this investigation is to relate cholinergic activity (CA) to objective measures of balance, gait, and attention in a MCI and control…Axial Myoclonus in a Patient with PSP
Objective: This is a case report from the Portland VA Medical Center. Background: PSP is a parkinsonian neurodegenerative disorder characterized by deposition of tau in…Structural brain changes in patients with Multi System Atrophy: A VBM and DTI based study.
Objective: To evaluate the grey matter (GM) and white matter (WM) changes in patients with Multiple System Atrophy (MSA) using MRI. Background: MSA is a…Loss of PDE10A expression in patients with PDE10A and ADYC5 mutations
Objective: To assess phosphodiesterase 10A (PDE10A) expression in vivo, using [11C]IMA107 PET in patients with PDE10A and adenylate cyclase 5 (ADYC5) mutations. Background: Cyclic adenosine…The highly-selective metabotropic glutamate receptor 2 positive allosteric modulator LY-487,379 alleviates psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset
Objective: To investigate the effect of metabotropic glutamate receptor 2 (mGluR2) activation on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced psychosis-like behaviours (PLBs) and dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset…Network for parallel gamma synchronizations during upper limb movement
Objective: Our aim was to identify the sources of parallel gamma synchronizations (GS) and analyze the direction of information flow in their network, at the…Risk Factors for Dementia in Parkinson’s disease
Objective: To investigate putative risk factors for the development of dementia in patients with Parkinson’s disease. Background: Dementia in idiopathic Parkinson’s disease (PD) is a…Action Verb Generation as a marker of cognitive function in Parkinson disease
Objective: We investigated action-verb generation in relation to cognitive function and motor severity in patients with Parkinson disease (PD). Background: PD causes speech and language…IGF-1 levels are associated with CSF pathology and executive dysfunction in de novo Parkinson’s disease patients
Objective: To investigate whether serum insulin-like growth factor-1 (IGF-1) is associated with clinical-neuropsychiatric, imaging and CSF markers of PD pathology in patients with early, drug-naïve…
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