Assessment of new technology in deep brain stimulation technology: what are the anticipated benefits?
Objective: To assess the ability of directional DBS leads and stimulation field shaping to provide more precisely targeted therapy. Background: Deep brain stimulation (DBS) has…Antisense oligonucleotides containing amido-bridged nucleic acid downregulate SNCA expression and improve motor function in Parkinson’s disease mouse models.
Objective: In this study, we used gapmer-type antisense oligonucleotides (ASOs) containing amido-bridged nucleic acid (AmNA). ASO, short single-stranded stretches of DNA or RNA with complementary…Combined Motor and Cognitive Training Improves Motor and Cognitive Function in People with Parkinson’s Disease and Freezing of Gait
Objective: Investigate whether combined motor and cognitive training improves motor and cognitive function in people with PD and freezing of gait (FOG). Background: FOG affects…Impact of weekly dance classes on quality of life of individuals with Parkinson’s Disease.
Objective: The aim of the present study is to investigate the short-term effects of weekly dance classes on the Quality of Life (QOL) of PD…A new neurophysiological tool for differential diagnosis in tremor syndromes: The Tremor Stability Index
Objective: We present a robust new neurophysiological measure, the Tremor Stability Index (TSI), which can discriminate Parkinson’s disease tremor (PD) and Essential tremor (ET) with…Effects of thalamic deep brain stimulation on posture and balance in patients with essential tremor
Objective: To characterize posture and balance dysfunction in patients with essential tremor (ET) after undergoing deep brain stimulation (DBS) of the thalamic nucleus ventralis intermedius…Induced pluripotent stem cells based in-vitro modelling of Spinocerebellar Ataxia type -12 (SCA-12).
Objective: To derive neuronal lineages from patient’s peripheral blood mononuclear cells (PBMCs) and exploration of disease biology. Background: Spinocerebellar ataxia type-12 (SCA-12) is a progressive cerebellar…Effectiveness of Deep Brain Stimulation (DBS) in Mice with Spinocerebellar Ataxia (SCA1).
Objective: To evaluate the effectiveness of Deep Brain Stimulation (DBS) in a mouse model of Spinocerebellar Ataxia type 1 (SCA1). Background: Spinocerebellar ataxia type 1…Delayed progressive spastic cerebellar ataxia and cerebellar atrophy after Heat Stroke
Objective: To describe a very rare case of delayed progressive spastic cerebellar ataxia after an episode of survival after heat stroke Background: Heat stroke is…Non-Progressive Coreoatethosis Secondary to Infantile Necrotizing Encephalopathy Mimicking Leigh Disease.
Objective: Our objective is to report image findings of an acute necrotizing encephalopathy of childhood (ANEC) in a 15 years-old girl, completely normal until 18…
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