Expression of late cell cycle markers in Parkinson Disease and Lewy Body Dementia
Objective: The objective of this study is to determine the expression of late cell cycle markers in Parkinson Disease (PD) and Lewy Body Dementia (LBD) Background:…Objective gait parameters as a noninvasive biomarker for freezing of gait in Parkinson’s disease patients
Objective: To determine if steady-state gait parameters in Parkinson disease (PD) patients could serve as a predictive biomarker for freezing of gait (FOG). Background: FOG…Inhibition of long term memory and induction of biochemical deficits in rats following protofibrillar Aβ 1-42 injection
Objective: The present study was undertaken to study the effects of single intracerebroventricular (i.c.v.) injection of protofibrillar Aβ 1-42 on the long term memory Background:…An unusual presentation of tyrosine hydroxylase deficiency
Objective: To discuss a case of tyrosine hydroxylase deficiency presenting with resolution of symptoms on levodopa except for a dynamic segmental dystonia Background: Dopa-responsive dystonia…Abnormal activity in reward system in Parkinson’s disease patients with rapid eye movement sleep behavior disorder
Objective: To study the mesocorticolimbic reward system in Parkinson's disease (PD) patients with and without REM sleep behavior disorder (RBD). Background: RBD is a parasomnia…The Personal Kinetigraph Fluctuator Score Identifies Motor Fluctuations in Parkinson’s disease
Objective: To evaluate the Personal Kinetigraph (PKG) fluctuator score (FS) in detecting motor fluctuations in Parkinson's disease (PD) patients. Background: Fluctuations of response to levodopa,…Patient Clustering through a Mobile-based PD Severity Score
Objective: To demonstrate that PD patients can be clustered based on their performance on smartphone-enabled active tests. Background: Treatment decisions of PD require granular information…Istradefylline improves motor symptoms in Parkinson’s disease: A meta-analysis
Objective: The aim of this meta-analysis was to provide strong evidence for the main and side effects of istradefylline on patients with Parkinson’s disease. Background:…Targeting alpha-Synuclein Aggregation for the Treatment of Parkinson’s Disease
Objective: To develop small molecular weight compounds (SMEs) as disease-modifying agents, which are designed to arrest or even reverse the aggregation process of alpha-synuclein (aSyn)…Intranasal delivery of insulin for the restoration of memory signaling in Alzheimer disease
Objective: Objective of this study is to develop delivery-system to overcome BBB by employing novel, non-invasive approach via nasal route. The olfactory neural pathway provides…
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