A randomized, double-blind, placebo-controlled study of the D1 receptor antagonist ecopipam for children and adolescents with Tourette syndrome
Objective: To investigate the efficacy and safety of the selective dopamine D1 receptor antagonist ecopipam in children and adolescents with Tourette Syndrome (TS). Background: Dysregulation…Clinical and demographics of cervical dystonia related to the direction of the neck movement
Objective: The objectives of this report is to survey whether the type of torticollis (i.e. rotation, retrocolis and anterocolis) is related to the clinical characteristics…Dystonia-like phenotype in a DYT1 rat model after peripheral trauma
Objective: Establishment and characterization of a DYT1 rat model with dystonia-like movements after sciatic nerve crush injury. Background: Penetrance of DYT1 dystonia is markedly reduced…The Volatility of Local Field Potential Oscillations in Dystonia and Parkinson’s disease
Objective: To assess the volatility of low frequency (4-12Hz) and beta-band (13-30Hz) oscillations in local field potentials (LFPs) in dystonia and compare this to LFPs…Trisomy 8 Mosaicism and dystonia: a THAP1 overdose?
Objective: We report a case of Trisomy 8 Mosaicism (T8M, Warkany Syndrome) with craniocervical and hand dystonia, an hitherto unreported disease association. Background: T8M is…Differences between Hemifacial spasm with or without neurovascular conflict. Therapeutic implications with botulinum toxin type A.
Objective: To evaluate the presence of possible clinical differences between patients with HS with and without neurovascular conflict (NVC +, NVC-) and their therapeutic response…Self Perception of Dysphagia in Parkinson Disease
Objective: To determine when individuals with Parkinson disease (PD) perceive impairment of swallowing as it relates to time since diagnosis. Background: Dysphagia, and particularly silent…Polyneuropathy in patients with Parkinson’s disease from southern Spain treatment with levodopa/carbidopa intestinal gel infusión
Objective: This study main objective is to prospectively report the 10-year incidence of polineuropathy in Parkinson´s disease patients from southern Spain treated with LCIG. Background: Patients with…Ocular Motor Disorders Among Filipino “LUBAG” or X-Linked Dystonia Parkinsonism (XDP) Patients
Objective: To determine the prevalence of ocular motor disorders among X-Linked Dystonia Parkinsonism (XDP) patients seen in Jose R Reyes Memorial Medical Center, and at…Safety of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: Preliminary Results from a Phase III Study
Objective: To determine the safety of single treatments of APL-130277 in patients with Parkinson’s disease (PD). Background: Patients with Parkinson’s disease (PD) frequently develop problematic…
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