Voluntary suppression of Parkinson’s tremor
Objective: To provide the first detailed systematic investigation of the phenomenon of voluntary tremor suppression in Parkinson’s disease (PD). Background: We have observed in the…Phenotypic variability of essential tremor based on the age at onset
Objective: To explore the distribution of the AAO of essential tremor based on mathematical modeling and ascertain differences in the clinical features of subgroups. Background:…Role of Sex on Cholinergic Activity and Attention in Parkinson’s disease
Objective: To determine whether cholinergic activity related to attention differs in males versus females in people with Parkinson’s disease (PwPD). Background: Although cholinergic activity is…The effects of sensory reward cues on risky decision making in Parkinson’s disease
Objective: To evaluate the effects of sensory reward cues on risky decision making in unmedicated and medicated Parkinson’s disease (PD). Background: Cue reactivity may play…Clinical predictors of screen-defined dementia in early Parkinson’s
Objective: Predicting early dementia in Parkinson’s disease (PD) has important implications for individual prognosis, designing clinical trials and targeting novel treatments, but there remains a…Exploring the relationship between motor impairment, vascular burden and cognition in Parkinson’s disease
Objective: To determine frequency and type of cognitive disorders in cross-sectional analysis of a Parkinson’s disease (PD) cohort, and explore its relations to motor symptoms,…FDG-PET and metabolomics in PD-associated GBA variants
Objective: To assess the clinical, cognitive, metabolic, and imaging phenotypes of PD patients carrying the variants p.E365K and p.T408M in the GBA gene (NM_000157.3). Background:…MANF improves the MPP+/MPTP-induced Parkinson’s disease via improvement of mitochondrial function and inhibition of oxidative stress
Objective: This study aimed to investigate the therapeutic effect of mesencephalic astrocyte-derived neurotrophic factor (MANF) on the MPTP/MPP+-induced model of Parkinson's disease (PD) and the…Expanding the canvas of PARKIN mutations and clinical phenotypes in familial and early onset Parkinson’s disease patients
Objective: To identify PARKIN mutations in PD patients with familial history (FPD) and early onset PD patients with no family history (EOPD; ≤50 years) and…BDNF(V66M), EIF4G1(R1205H), VPS35(D620N) gene polymorphisms in South Indian PD Patients
Objective: To investigate the association of BDNF(V66M), EIF4G1(R1205H) and VPS35(D620N) polymorphisms in South Indian PD patients. Background: Parkinson’s disease (PD) is the most common form…
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