Contribution of individual motor signs to striatal dopamine deficiency in parkinsonism
Objective: The primary aim of the study was to investigate if any individual motor sign could be used clinically to predict striatal dopamine deficiency. Secondary…A comprehensive digital biomarker active testing and passive monitoring suite for the remote and frequent assessment of motor symptom progression in Parkinson’s disease
Objective: We present the development and design of a comprehensive digital biomarker smartphone application (app) for remote and frequent assessments of motor symptom severity and…Altered putamen and cerebellum connectivity between different subtypes of Parkinson’s disease
Objective: we investigate the functional connectivity (FC) patterns of the putamen between different subtypes of PD) and healthy controls, and explore its clinical significance. Background:…Discriminating Idiopathic PD Patients and Controls in PPMI Using Integrative Multi-Modal Neuroimaging Analysis with Graph Convolutions
Objective: To discriminate Parkinson’s disease (PD) patients and controls in the Parkinson’s Progression Markers Initiative (PPMI) cohort according to MRI features using a novel a…What happens when I watch a ballet? Preliminary fMRI findings on somatosensory empathy in Parkinson Disease
Objective: To investigate the neural components of the mirror sensor-motor system recruited by a dance movement in a motor disorder, such as PD is. Background:…Executive Function and Frontoparietal Network Association in Freezing of Gait
Objective: To investigate the relationship between executive function and frontoparietal network (FPN) functional connectivity in Parkinson’s disease patients with freezing of gait (PD-FOG). Background: FPN…Anti-glutamatergic effect of safinamide in Parkinson’s Disease: A TMS study
Objective: To test the effect of safinamide, at the doses of 50 and 100 mg/day, on primary motor cortex (M1) excitability and glutamatergic neurotransmission in…Non-Motor Symptom In Young Onset Parkinson Disease as a Cause of Pharmacoresistence In Epilepsy
Objective: To report an interesting initial presentation of PD causing refractory epilepsy. Background: A lady with refractory depression, presented with first seizure at age 42,…Retinal and choroidal changes in autosomal recessive PD are similar to idiopathic PD
Objective: Our aim is to evaluate the structural changes in retina and choroid by Optical Coherence Tomography (OCT) in idiopathic Parkinson's disease (PD) and common…Impulse control disorders and compulsive behaviours in Parkinson’s disease. Results from the COPPADIS Study Cohort
Objective: Our objective was to analyze the existence of impulse control disorders (ICDs) and compulsive behaviours (CBs) in Parkinson’s disease (PD) patients compared to control…
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