Odor identification in PD patients and controls in Estonian cohort
Objective: To evaluate odors that discriminate Parkinson patients from healthy persons. Background: More than 90% of PD patients are diagnosed with olfactory impairment. The investigation…Progression of sleep disorders spectrum in Parkinson’s Disease: A 5 year clinical longitudinal study
Objective: To investigate longitudinal changes in the prevalence of different sleep disorders in the PPMI cohort of patients with Parkinson’s Disease (PD). Background: Sleep disturbances…Salivary Alpha-Synuclein and tau in Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: The aim of this study is to measure alpha-synuclein (a-syn) total, a-syn oligomers (a-syn olig) and total tau protein concentration in the saliva of…Frontal-subcortical cognitive impairments in Parkinson’s patients with freezing of gait
Objective: To evaluate the relationship between frontal-subcortical cognitive dysfunctions and freezing of gait (FOG) in Parkinson's disease (PD). Background: FOG is a complex and multisystem…The increased α-syn expression inhibits exosomal secretion
Objective: Exosomes, nano-sized extracellular vesicles, play an important role in many physiological processes in the central nervous system. Recently, we and others have demonstrated that…Soluble TREM2 and Central and Peripheral Inflammatory Biomarkers in Parkinson’s Disease
Objective: Given that Parkinson's disease (PD) may be associated with TREM2 and given that a soluble TREM2 (sTREM2) isoform has been described as elevated in…Association between serum Vitamin D levels and Parkinson’s disease: A systematic review and meta-analysis
Objective: The aim of this systematic review and meta-analysis was to evaluate the association between serum vitamin D levels and the risk and severity of…Quantitative Keyboard Tapping Measurement Correlates with Electrophysiological Changes in STN LFPs of PD Patients Treated with L-dopa Better Than UPDRS Subscores
Objective: Reliable and objective assessment of the symptoms of patients with Parkinson’s disease (PD) and the correlation of the measures with neural patterns is important…Saccades in Parkinson’s disease: Hypometric, slow, or maladaptive?
Objective: Quantitatively study visually-guided saccades (VGS) in Parkinson’s disease (PD). Background: Visuomotor deficits such as hypometric VGS are present in PD despite the retained ability…Evaluation of Parkinson’s Disease Psychosis Requires Structured Questioning of Patients and Caregivers
Objective: To determine the relationship between the patient and caregiver experience of the psychotic features of Parkinson's disease psychosis (PDP) reported to call center healthcare…
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