Automated Differential Diagnosis of Parkinsonian Syndromes Using FDG-PET Metabolic Brain Network Analysis
Objective: To discriminate among parkinsonian patients using an automated network analysis of FDG-PET brain images. Background: Clinical differentiating among parkinsonian syndromes: Parkinson’s disease (PD), multiple…Longitudinal decline in white matter integrity in Parkinson’s disease: An analysis of Parkinson Progression Markers Initiative diffusion tensor imaging data
Objective: To determine the relative changes in white matter integrity as measured by diffusion tensor imaging (DTI) magnetic resonance imaging (MRI) in PD patients relative…Structural neural correlates of independent gait domains in Parkinson’s disease
Objective: To assess the subcortical motor structures of the brain associated with independent gait domains from Lord et al’s gait models (1, 2), in Parkinson’s…Striatal dopamine uptake and olfactory dysfunction in patients with early Parkinson’s disease
Objective: To identify dopamine transporter status of corpus striatum and thalamus using magnetic resonance imaging-guided spatial normalization method in patients with PD according to olfactory…Hypometabolism of the posterior parietal cortex in PD with dementia: [18F]FDG PET study
Objective: To investigate the neuroimaging marker for dementia in Parkinson’s disease (PD) patients using [18F]FDG PET. Background: Dementia may occur in patients with PD during…Study on feasibility to develop a central nervous system (CNS) Leucine-rich repeat kinase 2 (LRRK2) PET tracer
Objective: To assess feasibility of developing a CNS LRRK2 PET tracer. Background: LRRK2 enzyme belongs to the leucine-rich repeat kinase family. Pathogenic mutations in the…Evaluation of bradykinesia in Parkinson’s disease using a computerised evolutionary algorithm
Objective: Application of a computerised algorithm to kinematic motor recordings to distinguish parkinsonian bradykinesia from normal movement. Background: Bradykinesia, the only obligatory physical sign for…Combined Neurite Orientation Dispersion and Density Imaging and Myelin Imaging Provide New Insights to White Matter Changes of the Neurocognitive-psychiatric Disorder in Parkinson’s Disease
Objective: To identify white matter (WM) changes in PD with neurocognitive-psychiatric symptoms (NPS) using neurite orientation dispersion and density imaging (NODDI) and magnetization transfer saturation…Validation of the new diagnostic criteria for fatigue in Parkinson’s disease
Objective: The aim of this study was to validate the new diagnostic criteria for fatigue1 in Parkinson’s disease patients. Background: Case definition and diagnostic criteria…Burden of Eye disease in Parkinson’s disease (PD)
Objective: To review the burden of eye pathologies in patients with Parkinson’s disease. Background: Parkinson’s disease and eye problems are common in older patients. Alterations…
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