Longitudinal alpha-synuclein in cerebrospinal fluid in early Parkinson’s disease, prodromal PD and healthy controls
Objective: To examine the longitudinal relationships between total alpha-synuclein (aSyn) changes in cerebrospinal fluid (CSF), clinical measures, and factors that may influence CSF aSyn in…Parkinson’s disease-related non-motor features as risk factors for post-operative delirium in spinal surgery
Objective: We investigated the association between PD-related NMSs and postoperative delirium in old people undergoing elective spinal surgery. Background: The clinical features of postoperative delirium…C-spine injury with progressive gait difficulty, drop foot, bizarre gait and serum positive stiff person syndrome: A case report
Objective: A complicated case presented with trauma history and insidious onset of stiff person syndrome. Background: Stiff person syndrome is a rare neurological disorder characterized…Reversible Extrapyramidal features as unusual presentation of central pontine myelinolysis: A case report
Objective: To be acquainted with the extrapyramidal symptoms developed during the course of central pontine myelinolysis. To emphasize the importance of neuroimaging in the diagnosis…A case of levodopa responsive rapid onset dystonia-parkinsonism
Objective: We describe and demonstrate by video a young man with rapid onset dystonia parkinsonism who has a robust response to levodopa. Background: Rapid onset…Methylphenidate in Progressive Supranuclear Palsy [PSP] – Old drug, New Indications?
Objective: To evaluate whether Methylphenidate can improve some symptoms of PSP. Background: PSP is a neurodegenerative disorder with limited therapeutic options. Methylphenidate[MPH] , a drug…The role of substantia nigra sonography in the differentiation of Parkinson’s disease and multiple system atrophy
Objective: To evaluate the differential diagnosis value of transcranial sonography (TCS) between Parkinson’s disease (PD) and multiple system atrophy (MSA) Background: The differential diagnosis of…Disease progression and survival of multiple system atrophy: A prospective French cohort study
Objective: We report the first prospective natural history study of MSA combining progression of the disease and mortality. Background: Multiple system atrophy (MSA) is a…Gait and balance assessment in Hoehn and Yahr stages of Parkinson’s disease using Smartphone-based instrumental Timed Up and Go
Objective: To introduce 'APPTUG', a smartphone-based instrumental Timed Up & Go (TUG) test, and to study its ability to discriminate between the stages of Parkinson's…Retrospective study on a cohort of 285 PD patients: Does the side of onset influence the global clinical phenotype?
Objective: To describe demographic and clinical characteristics of a cohort of 285 consecutive PD patients and to understand the phenotypic differences of right onset (RPD)…
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