Bipolar directional DBS in VIM-stimulated patients
Objective: To compare circular, directional and bipolar stimulation in VIM-implanted PD- and ET-patients regarding effect and side-effect thresholds in a cross-sectional design. Background: So far,…Therapeutic exposures of CX-8998, a potent, selective and state dependent Cav3 channel antagonist in development for Essential Tremor and Parkinson’s disease Tremor in Cav3 driven neurological models
Objective: In this study, we utilized preclinical data to establish predicted human therapeutic exposures of the potent, selective and state-dependent Cav3 channel antagonist, CX-8998, currently…The Research of the Structural Changes of Cerebellar Tissue in Tremor-type Parkinson’s Disease Based on DKI
Objective: Using Diffusion Kurtosis Imaging (DKI) to observe the structural changes of the cerebellum in patients with tremor-type Parkinson’s Disease (PD), and to provide a…An open labeled, observational study for the Satisfaction and Preference of the Rivastigmine patch for treatment of Alzheimer’s disease and Parkinson’s disease dementia (SAFE-ADPD) in Koreans
Objective: This study performed to access caregiver’s satisfaction and preference of the Rivastigmine patch for treatment of Alzheimer’s disease and Parkinson’s disease dementia patients to…Fasciculations from a cholinesterase inhibitor
Objective: Present and discuss fasciculations in the setting of acetylcholinesterase inhibitors. Background: Specific acetylcholinesterase (AChE) inhibitors (e.g., donepezil, rivastigmine, galantamine) are the current first-line treatment…Clinical profile and predictors of outcome in Neuroleptic malignant syndrome and Parkinsonism hyperpyrexia syndrome
Objective: To assess the clinical profile and the factors predicting mortality of Indian patients with Neuroleptic malignant syndrome(NMS) and Parkinsonism hyperpyrexia syndrome (PHS). Background: NMS…Attitudes to Palliative Care in Movement Disorder Physicians in the UK
Objective: The objective of this project was to determine attitudes toward palliative care (PC) of physicians in the UK who manage movement disorder. Care of…A novel mutation in VRK1 associated with distal spinal muscular atrophy
Objective: To elucidate the underlying genetic cause of dSMA in a Chinese family with two affected siblings. Background: Distal spinal muscular atrophy (dSMA), also called…Cervical dystonia in Modigliani’s paintings: The clue was the sensory trick
Objective: To confirm that Jeanne Hebuterne, Modigliani's muse, suffered from cervical dystonia Background: Amedeo Modigliani was one of the most outstanding painters of the XX…Caudate nucleus atrophy as an early finding of Neuroferritinopathy
Objective: To report the presence of caudate nucleus atrophy from early stages of Neuroferritinopathy. Background: Neuroferritinopathy is a form of neurodegeneration with brain iron accumulation,…
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