What can we learn from fMRI capture of visual hallucinations in Parkinson’s disease?
Objective: To describe the patterns of brain functional changes when visual hallucinations (VH) occur in patients with Parkinson's disease (PD). Background: With disease progression, PD…A Psychometric Analysis of the MDS UPDRS-II and III in Early Parkinson’s disease: Do the Numbers Add Up?
Objective: Our objective was to explore the psychometric evidence for the use of the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) part II…A German-Austrian multicenter, non-interventional, prospective study for the treatment with abobotulinumtoxinA injections in naïve and previously treated patients suffering from cervical dystonia
Objective: In this prospective, multicenter, non-interventional study (NCT01840462) the primary objective was effectiveness of abobotulinumtoxinA in BoNT treatment-naïve and previously treated subjects after two injection…Safinamide in Parkinson’s disease
Objective: To evaluate clinical effects, safety and tolerability of safinamide add-on levodopa in Parkinson’s disease (PD) patients. Background: Safinamide is a recently approved adjunctive treatment…Open-label extension (OLE) of a multiple ascending dose (MAD) study of BIIB092 in participants with PSP: Safety analysis
Objective: To assess safety of BIIB092 in participants with progressive supranuclear palsy (PSP) in an OLE of a MAD study. Background: BIIB092 is a humanized…Cognitive effects of SIRT6 overexpression: Emerging role of astrocytes
Objective: The aim of this work was to elucidate the effect of SIRT6 overexpression on cognition. Background: Recent evidence show that astrocytes are important for higher brain…Tardive Myoclonus: A Case Report
Objective: To report a patient with late-onset myoclonus after treatment with antipsychotic drugs which is a rare variant of tardive movement disorders. Background: The use…Effects of PGE inhibition on Striatal Neuroinflammation in 6-OHDA lesion
Objective: In this study, we investigated the role of prostaglandin E2 inhibition, pro-inflammatory cytokine concentration and microglial activation in a Parkinsonian rat Background: Neuro-inflammation plays…Educating Movement Disorders through a web based counselling service in Mauritius
Objective: The provision of solutions and relevant information to the general public and mostly to young people is the way forward to help the elderly…Familial SCA2-parkinsonism presented as intractable oromandibular dystonia
Objective: We report a patient of spinocerebellar ataxia type 2(SCA2)-parkinsonism family who developed oromandibular dystonia as the chief presentation. Background: We previously described a Korean…
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