Carbon Monoxide Poisoning-Induced Parkinsonism: A Prospective Study of Clinical and Neuroimage Correlation
Objective: To investigate prospectively the nigrostriatal system in patients with delayed post-anoxic Parkinsonism by TRODAT-1 brain SPECT serially and to correlate the neuropsychiatric performance and…Patterns of dopamine transporter imaging in subtypes of Multiple System Atrophy
Objective: To investigate the differences in the pattern of striatal (caudate and putamen) dopamine transporter(DAT) loss in a multiple system atrophy (MSA) cohort, based on…Neuroprotective effects of coffee ingredients against rotenone-induced neurodegeneration in parkinsonian model
Objective: In this study, we examined neuroprotective effects of coffee ingredients, caffeic acid (CA) and chlorogenic acid (CGA), against rotenone-induced neurodegeneration using primary cultured cells…Novel biomarkers of autonomic regulation and sleep in Parkinson’s Disease derived from Network Physiology
Objective: Utilize a novel Network Physiology approach to identify new biomarkers of Parkinson’s Disease (PD) based on the dynamics on individual physiological systems, and their…Emulating the natural timing of dopamine receptor activation in Parkinson’s Disease
Objective: To emulate physiological dopamine receptor activation, in order to restore temporal patterns of dopamine-like signalling and normalise function in the striatum in Parkinson's disease.…Impact of SYN120 (a Dual 5-HT6/5-HT2A antagonist) on psychiatric symptoms in patients with Parkinson’s disease dementia: Results from a Phase 2a Study
Objective: To assess the psychiatric effects of SYN120 in patients with Parkinson's disease dementia (PDD). Background: SYN120 is a dual antagonist of serotonin (5-HT6 and…Ambulosono – A Music Walking Program Improves Gait Disorders in Parkinson’s Disease
Objective: The aim of the study was to study the effect of Ambulosono - a music walking program on the walking ability of patients with…Development of anti-amyloid drugs for Parkinson’s disease by combination screening of high-throughput in vitro assay and phenotype-based C. elegans system
Objective: To establish a new combination screening system consisted of high-throughput in vitro assay with phenotype-based in vivo assay and to develop anti-amyloid drugs truly…Update on The Personalized Parkinson Project: Partnering with Patients to Understand Disease Progression Through a Multi-Dimensional Approach
Objective: Enrollment for The Personalized Parkinson Project (PPP) is underway. Co-design and mutual partnership between patients and researchers is a key characteristic of the project…Safinamide effect in patients with Parkinson’s disease and deep brain stimulation
Objective: Aim of this retrospective study is to evaluate safety and efficacy of safinamide in the treatment of motor complications in patients with Parkinson’s Disease…
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