STEEred vs RING-mode Deep Brain Stimulation for Parkinson’s disease: STEERING trial
Objective: To evaluate whether directional STN DBS is more effective than ring-mode DBS in reducing PD motor symptoms, and to investigate if directional STN DBS…Impact of Age on Levodopa dosage regimes in Idiopathic Parkinson’s Disease
Objective: To assess the influence of patient age on prescribed dosage and subsequent dose escalation regimes of levodopa therapy in a cohort of people with…Effectiveness of a Multi-disciplinary Parkinson’s Disease (PD) Clinic: A 2-year Prospective Observational Study
Objective: To evaluate if a multi-disciplinary PD clinic can result in better outcome in PD patients in 2 years. Background: PD is a neurodegenerative disease…Movement Disorders Phenomenology in Focal Motor Seizures
Objective: To examine the extent to which focal motor seizures can present with a phenomenology fulfilling diagnostic criteria for one or more movement disorder. Background:…Is early onset ataxia phenotypically discernible from developmental disorders with impaired coordination?
Objective: To investigate: 1. the diagnostic accuracy of phenotypic Early Onset Ataxia (EOA) recognition among other pediatric disorders with impaired coordination (developmental coordination disorder (DCD)…Parkinsonism in Christianson Syndrome: A Unique Presentation of a Unique Syndrome
Objective: Phenotypic variability in Christianson Syndrome Background: The SLC9A6 gene encodes a sodium-hydrogen exchanger-6 protein involved in endosomal trafficking. Loss-of-function variants in SLC9A6 gene have…A novel homozygous splice site mutation in the KIF1C gene (SPAX2, SPG58) found in a consanguineous turkish family
Objective: We present clinical, electrophysiological and genomic data of a consanguineous family with two affected siblings suffering from spasticity and severe ataxia. Background: Mutations in…Targeting GPi: DBS Treating Dystonia in a Patient with Wilson’s Disease
Objective: The primary objective is to determine the efficacy of Deep Brain Stimulation (DBS) targeting the internal segment of the globus pallidus (GPi) on treating…The change of heart rate variability after subthalamic nucleus deep brain stimulation in patients with Parkinson’s disease: A Meta⁃analysis
Objective: To evaluate the changes of heart rate variability (HRV) after subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s disease (PD). Background: The…Directional DBS: A new algorithm to determine lead rotation
Objective: To establish a pipeline for reliable determination of lead rotation in directional DBS. Background: New directional leads with segmented electrodes are now widely used…
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