Exosomal alpha synuclein secretion is beneficial for cellular models of Kufor-Rakeb syndrome
Objective: The purpose of this study is to investigate the effect of induction of exosomal a-syn secretion on PARK9-mediated neurotoxicity. Background: Kufor-Rakeb syndrome (KRS) is…Biological course and natural history of hereditary spastic paraplegia type 11 (SPG11)
Objective: We aim to establish biological markers for the natural history and course of hereditary spastic paraplegia (HSP) type 11 (SPG11) using multiple readout parameters…Patient with secondary dystonia treated with internal globus pallidus deep brain stimulation (GPi-DBS), 2 years results: A case report
Objective: To assess long term benefit of multiple source steering of GPi-DBS in a patient with secondary dystonia due to kernicterus related perinatal encephalopathy. Background:…Optimizing the Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) outcome in Parkinson’s disease patient with interleaving stimulation
Objective: To explore interleaving versus conventional stimulation in subthlalmic nucleus (STN) deep brain stimulation (DBS) in optimizing the effect. Background: STN DBS is effective for…Programming for Freezing of gait after Bilateral Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s Disease
Objective: Freezing of gait (FOG) is a common gait disorder in Parkinson's disease (PD). In this study, we will adjust programming for patients with FOG…A prospective MRI study of edema surrounding deep brain stimulation leads
Objective: The purpose of our study is to define the incidence and the magnetic resonance imaging (MRI) characteristics of peri-electrode edema in a cohort of…Can brittle dyskinesia be one of the causes of Twiddler syndrome in Deep Brain Stimulation?
Objective: To discuss whether brittle dyskinesia can be a cause of Twiddler syndrome. Background: Many studies have reported that the cause of Twiddler syndrome (…Subthalamic deep brain stimulation is safe and effective treatment for elderly patients with Parkinson’s disease
Objective: To investigate the safety and efficacy of subthalamic nucleus (STN) deep brain stimulation (DBS) in elderly patients with Parkinson's disease (PD). Background: Even though…Bilateral stereotypy after unilateral cerebellar infarction
Objective: To report a case with bilateral hand stereotypy after left cerebellar infarction Background: Stereotypy is defined as repetitive and continuous non-goal-directed movement. It was…Acute Stroke in Middle Cerebellar Peduncle in a Patient with FXTAS
Objective: Report a case of Fragile X associated Tremor/Ataxia Syndrome (FXTAS) with acute middle cerebellar peduncle (MCP) infarction, and highlight the potential susceptibility of the…
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