Assessing the potential of EEG as a biomarker in Huntington’s disease using machine learning automatic classification
Objective: To construct an automatic classifier distinguishing healthy controls from Huntington’s disease (HD) gene carriers using quantitative electroencephalography (qEEG) and to derive qEEG features that…Predicting Alpha-Synuclein Pathology by REM Sleep Behavior Disorder Diagnosis
Objective: Determine sensitivity, specificity and predictive value of clinician diagnosed probable REM sleep behavior disorder (PRBD) in predicting alpha-synuclein pathology. Background: Inability to accurately diagnose…Parkinsonism with rare sequence variants in VPS35 and FBXO7 genes associated with Lewy body pathology
Objective: To detect a neuropathological background of parkinsonism associated with rare sequence variants in the VPS35 and FBXO7 genes. Background: A total of 23 gene…Adolescent onset RBD converting to PD after 48 years
Objective: To present a patient with adolescent onset dream enactment behaviour who developed PD 48 years later. Background: RBD typically occurs after age 50, and…Rotenone model of Parkinson’s disease: The dosing options in mice revisited
Objective: In the present study we have used various dosing protocols to induce the PD-like symptoms with the administration of rotenone in mice. Background: Parkinson's…Approaching Health Care Shaped by Generational Expectations (The AGE Study): Generational Perspective Related to Time
Objective: To investigate the preferences different generational groups (i.e. Traditionalists, Baby Boomers, Generation X-ers, and Millennials) have towards healthcare with regards to time management. Background:…Apolipoprotein E and multiple system atrophy
Objective: This study evaluated genetic associations of Apolipoprotein E alleles with risk of multiple system atrophy (MSA) and α-synuclein pathology, and also examined whether apolipoprotein…[18F]FP-CIT and [18F]FDG PET findings in MSA patients with cognitive impairment
Objective: We investigated the brain dopaminergic system and glucose metabolism in multiple system atrophy (MSA) patients with cognitive impairment. Background: Since the first report of…Accuracy of the International Parkinson Disease and Movement Disorder Society Progressive Supranuclear Palsy Diagnostic Criteria (IPD-MDS-PSP)
Objective: To evaluate the accuracy of the IPD-MDS-PSP criteria to differentiate PSP-Richardson (PSP-R) from PSP-parkinsonism (PSP-P), the most common PSP phenotypes. Background: The new International…Patient Perspective in Multiple System Atrophy
Objective: To report patient and/ or caregiver perspective in Multiple System Atrophy (MSA). Background: The majority of literature on MSA’s natural history comes from single…
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