Chitotriosidase is a biomarker for Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)
Objective: ALSP belongs to the large group of rare neurogenetic, adult-onset leukodystrophies. For most of these leukodystrophies, including ALSP, no causative treatment exists. Biomarkers facilitate…Deep brain stimulation: A Treatment Modality for Generalized Dystonia Secondary to Anoxic Brain Injury in Adults
Objective: To report a case of severe generalized dystonia secondary to anoxic brain injury treated successfully with bilateral globus pallidus interna (GPi) deep brain stimulation…Comparison of Mattis and MOCA testing for neuropsychological assessment in the preoperative evaluation of subthalamic nucleus stimulation in Parkinson´s disease
Objective: The aim of the current study is to evaluate, whether 1. MOCA (Montreal Cognitive Assessment) and Mattis tests are equivalent in the detection of…Comparative results between preoperative acute levodopa challenge test and deep brain stimulation
Objective: Our aim is to compare motor clinical benefits after acute levodopa challenge test, with those obtained further with deep brain stimulation (DBS). Background: DBS…Deep brain stimulation for monogenic Parkinson’s disease: A systematic review
Objective: The aim was to systematically investigate the outcome of deep brain stimulation (DBS) in genetic Parkinson’s disease (PD) compared to the patients with documented…Long-term effect of low frequency stimulation of STN on dysphagia, freezing of gait and other motor symptoms in PD
Objective: To evaluate the long-term effect of 60Hz low frequency stimulation (LFS) of the subthalamic nucleus (STN) on dysphagia, freezing of gait (FOG) and other…Directional DBS; clinical experience at Unit of Functional Neurosurgery. Ramón y Cajal University Hospital,Madrid, Spain
Objective: to determine the practicabillity of using an image guide programming setting in our clinical practice. Background: The applicability of DBS leads and systems that…Deep Brain Stimulation in Tourette Syndrome: Two illustrative cases
Objective: To describe two cases of patients with pharmacological refractory Tourette syndrome who underwent DBS in a single center in Bogota Colombia from 2012 -2015.…Cerebrotendinous Xanthomatosis: A Rare Lipid Storage Disease
Objective: Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive lipid storage disease. It is caused by the deficiency of mitochondrial enzyme sterol 27-hydroxylase due to…Evaluation of Balance in Hereditary Ataxias
Objective: To describe and compare the vestibular findings most evident among the hereditary ataxia, as well as correlate their clinical aspects to the study of…
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