Medical management after subthalamic nucleus deep brain stimulation in patients with Parkinson’s Disease
Objective: The present study aims to: i) systematically evaluate literature data on acute medical management after subthalamic nucleus (STN) deep brain stimulation (DBS) and, ii)…Safety and Tolerability of opicapone in Parkinson’s disease
Objective: To evaluate safety and tolerability of opicapone as an add‐on treatment to levodopa in Parkinson's disease (PD) patients. Background: Opicapone is a recently approved…Gender differences of fatigue characteristics in people with Parkinson’s disease
Objective: To investigate gender differences in fatigue characteristics in people with Parkinson’s disease. Background: Fatigue is a common problem among people with Parkinson’s disease. It…Language disorders in Progressive Supranuclear Palsy: an underestimated condition?
Objective: We aimed to investigate executive functions and languages abilities in PSP patients and in Progressive Supranuclear Palsy (PSP) subgroups [PSP-Richardson’s Syndrome (PSP-RS) and PSP-non-RS]…Levodopa response in later stages of Parkinson’s disease: a case-control study
Objective: To compare the response of motor and non-motor symptoms (NMS) to a L-dopa challenge test between late stage (LS) PD patients and advanced stage…Swallowing assessment in Parkinson’s Disease using Dynamic Magnetic Resonance Imaging (dMRI)
Objective: To evaluate any dysphagia-signs in Parkinson’s disease (PD) with technique that is non-invasive, without-radiation-exposure and gives good soft-tissue contrast. Background: Swallowing, a basic oromotor…Impaired lysosomal catabolism of alpha-synuclein in parkinsonian LRRK2(R1441G) mutant mouse embryonic fibroblasts
Objective: Using a unique fluorescence-based flow cytometry assay on LRRK2(R1441G) mutant mouse embryonic fibroblasts (MEFs) to elucidate whether pathogenic LRRK2 mutation affects cellular lysosomal degradation…Concomitant brain pathologies have no major impact on clinical milestones in progressive supranuclear palsy
Objective: To analyze the frequency and severity of co-pathologies in PSP patients and their relevance for the clinical presentation and progression in PSP. Background: The phenotypic…Progressive Parkinsonism and Cognitive Changes: A Rare Presentation of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS)
Objective: To describe a rare manifestation of a case of CLIPPERS with video-based documentation of treatment responsiveness. Background: CLIPPERS is a rare inflammatory disease of…Comorbid Parkinson’s disease and Myasthenia Gravis: A Case-Control Study
Objective: To evaluate the clinical features of patients with Parkinson’s Disease (PD) with versus without comorbid Myasthenia Gravis (MG). Background: The recognition of the co-occurrence…
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