Opicapone added to safinamide in patients affected by Parkinson’s disease for better controlling motor fluctuations
Objective: The aim of this clinical observation was to verify the sparing of levodopa in patients affected by Parkinson's disease who already started safinamide treatment for…Efficacy and safety of the 5-Hydroxytryptophan on Depression and Apathy in Idiopathic Parkinson’s disease.
Objective: The purpose of this study was to compare the effects of 5-HTP to placebo on depression and apathy in patients with PD. Background: Parkinson’s…Increasing chances of detecting a neuroprotective signal in PhI/II PD clinical trials?
Objective: Design an early CT program to detect a neuroprotective signal in PD. Background: Attempts to develop PD modifying therapies have been largely disappointing so…Effect of opicapone in Parkinson’s disease patients with ‘early’ motor fluctuations: Parkinson’s Disease Questionnaire (PDQ-39) analysis from the BIPARK-I double-blind experience
Objective: To evaluate the impact of opicapone (OPC) on PDQ-39 in levodopa-treated Parkinson’s Disease (PD) patients with ‘early’ motor fluctuations. Background: OPC, a once-daily COMT…Evaluating the Inappropriate Use of Antipsychotics in Parkinson’s Disease Psychosis Patients Within Large National US Healthcare Databases
Objective: To identify Parkinson’s disease psychosis (PDP) treatment characteristics from an aggregate of US national insurer and Medicare databases. Background: Treatment of psychotic symptoms associated…The relationship between the motor onset and the asymmetry of motor symptoms in patients with Parkinson’s Disease
Objective: The objective of our research was to study the relationship between the motor onset and the asymmetry of motor symptoms in patients with Parkinson’s…Dentatorubral-Pallidoluysian Atrophy outside of Asia: A case report of the first Austrian family harbouring this rare mutation
Objective: To report clinical features of the first Austrian family with Dentatorubral-Pallidoluysian Atrophy (DRPLA). Background: DRPLA is a progressive disorder with an autosomal-dominant mode of…Study of eye movements as a tool in the diagnosis hereditary ataxias
Objective: To study ocular movements (ocular pursuit, nystagmus and saccades) in the most frequent ataxias (SCA2, SCA3 and Friedreich's ataxia), to find out which variables…Think of Gluten Ataxia:A rare but potentially reversible cause of progressive neurological disorder
Objective: To explore an unusual cause of ataxia in a patient with known Celiac disease. Background: Celiac disease is the established but not the only…Paraneoplastic Cerebellar Degeneration As Initial Symptom Of Renal Cell Carcinoma
Objective: To describe a case of paraneoplastic cerebellar degeneration in a patient with renal cell carcinoma. Background: Paraneoplastic cerebellar degeneration belongs to a group of…
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