Sleep Aspects on Video-Polysomnography in P.A53T SNCA Mutation Carriers
Objective: To determine whether REM sleep behavior disorder (RBD) and other sleep abnormalities occur in carriers of the p.A53T alpha-synuclein gene (SNCA) mutation, the prototypical…Determining Outcome of Deep Brain Stimulation Surgery in Parkinson’s Disease Patients
Objective: To assess the role of monogenic forms of PD and polygenic risk scores (PRS) on the motor and cognitive outcome of deep brain stimulation…Digenic inheritance of WARS2 and CHRNA6 mutations in infantile parkinsonism
Objective: To provide evidence of digenic inheritance in infantile parkinsonism. Background: Oligogenic inheritance has been demonstrated in PD[1],where patients with a primary genetic cause can…Associations of Genetic, Epigenetic and Phenotypic Measures in the Dominican Republic PKAN Cohort
Objective: To explore relationships between demographic, clinical and behavioral phenotypes and underlying genetic and epigenetic features, utilizing a large cohort of PKAN patients. Background: PKAN…Different clinical entities of Segawa syndrome within a family
Objective: We report two cases of mother and daughter, both having different expressions of dystonic movements. Background: One of rare dystonic disorders is Segawa syndrome…Differential effects of stem cell therapy in adult and middle-aged Parkinsonian mice
Objective: To perform an in-depth analysis of the effects of transplanting neural stems cells in Parkinsonian mice. Background: Parkinson´s disease (PD) is the second most…Neuropsychological and behavioral profile of patients with isolated REM sleep behaviour disorders (iRBD) and patients with RBD associated with Parkinson’s Disease (PDRBD)
Objective: We aimed to compare the neuropsychological and psychobehavioral profile of patients with iRBD and PDRBD. Background: REM Sleep Behavior Disorder (RBD) is considered as…Modulation of the Startle Response in REM Sleep Behavior Disorder
Objective: To detect changes in the modulation of the Startle Reflex induced by brainstem circuitry abnormalities both in isolated and PD related Rem Behaviour Disorder…Beliefs, Knowledge and Attitudes Towards Parkinson’s Disease: Turkey Experience from a Global Perspective
Objective: To evaluate the knowledge, attitudes towards disease, and to assess the effect of beliefs on decision making among patients with PD, and their first-degree…Advanced Care Planning in complex Parkinson’s disease
Objective: To improve Advanced Care Planning in complex stage Parkinson’s disease Background: Parkinson’s disease is a common neurodegenerative condition progressing through diagnosis, maintenance, complex and…
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