NILO-PD: A Phase 2A Study of Nilotinib in Patients with Advanced Parkinson’s Disease: Study Design and Status Update
Objective: To assess the safety and tolerability of nilotinib (150-300 mg once daily) in moderate/advanced Parkinson’s disease (PD). Background: Nilotinib is approved by the FDA…Identification of candidates for device-assisted therapy in Parkinson’s disease using Artificial Neural Networks
Objective: To use Multilayer Perceptron (MLP), an artificial neural network, to identify candidates for device-assisted therapy (DAT) among patients with Parkinson's disease (PD) Background: DAT…Supportive treatments for Ataxia, a Randomized Control Trial
Objective: The objective of this study is to evaluate the effectiveness of supporting treatments that improve awareness and the quality of patient life and counsel…A homozygous pentanucleotide repeat expansion in cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS)
Objective: To identify the genetic cause in patients with CANVAS recruited at the University Hospital of Schleswig-Holstein, Campus Lübeck. Background: CANVAS is a late-onset neurological…Epidemiological study of multiple system atrophy: data from HoRC-MSA Project 2014-2019
Objective: To investigate epidemiological aspects of multiple system atrophy (MSA) in Hokkaido, Japan from the data of the Hokkaido Rare-disease Consortium for MSA (HoRC-MSA). Background:…Clinico-genetic correlation in 102 Spinocerebellar Ataxia Type 12 (SCA 12) patients
Objective: To report the phenotype among the largest number of genotypically confirmed SCA 12 patients. Background: SCA12 is an autosomal dominant cerebellar ataxia (ADCA) caused…Acute hemichorea in patient of uncontrolled type 2 diabetes mellitus; a case report with characteristic imaging
Objective: chorea is a rare complication of uncontrolled type 2 diabetes . we report a case of hyperglycemia, due to uncontrolled type 2 diabetes, presented…A retrospective analysis of clinical and electrophysiological characteristics of patients with myoclonus
Objective: We aimed to evaluate the clinical characteristics of patients with myoclonus and to identify the possible etiologies in different types of myoclonus based on…Ferroptosis, a recently identified cell death, as a therapeutic target for Parkinson’s disease.
Objective: We aim to determine in a cell model neuroprotective effects of targeting lipoxygenases (LOXs), central players in Ferroptosis, a novel regulated iron-dependent cell death…Evolution of anti-parkinsonian drug prescribing patterns in Parkinson’s disease
Objective: To compare Parkinson’s disease (PD) treatment practices by movement disorder (MD) specialists across a decade, and to determine the factors that influence drug choice…
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