MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Extrastriatal dopaminergic and serotonergic pathways in Parkinson’s disease and in dementia with Lewy bodies: a 123I-FP-CIT study

    A. Pilotto, F. Schianodicola, E. Premi, R. Grasso, R. Turrone, S. Gipponi, A. Scalvini, E. Cottini, B. Pagherà, V. Garibotto, MC. Rizzetti, L. Bonanni, B. Borroni, S. Morbelli, F. Nobili, UP. Guerra, D. Perani, A. Padovani (Brescia, Italy)

    Objective: To evaluate the common and divergent dopaminergic and serotonergic impairment in Parkinson's disease and dementia with Lewy bodies using 123I-FP-CIT imaging. Background: Striatal dopaminergic…
  • 2019 International Congress

    Sleep Disturbances in Essential Tremor: A pilot investigation of the related brain microstructural changes using diffusion tensor imaging

    YIL. Sengul, HAF. Otcu, ISM. Ustun, HAK. Sengul, ALP. Alkan (Istanbul, Turkey)

    Objective: In this pilot exploratory study, we aimed to search possible related brain microstructural changes of sleep disturbances (SD) in essential tremor  (ET) patients. Background:…
  • 2019 International Congress

    The Dutch Parkinson and Cognition study (DUPARC): Cognitive impairment and cholinergic innervation in de novo Parkinson’s Disease patients

    S. Vander Zee, JM. Boertien, MJJ. Gerritsen, JM. Spikman, T. van Laar (Groningen, Netherlands)

    Objective: To explore the incidence and characteristics of early cognitive impairment in Parkinson’s disease (PD) patients and the relationship with regional cholinergic innervation. Background: Cognitive…
  • 2019 International Congress

    Transcranial Photobiomodulation as an adjunct to Levodopa therapy in patients with Parkinson’s Disease; an open label pilot study

    H. Singh, N. Sawal (Chandigarh, India)

    Objective: To explore the effects of  transcranial Photobiomodulation (tPBM) on symptoms of Parkinson's Disease and establish this therapy's efficacy as an adjunct to Levodopa. Background:…
  • 2019 International Congress

    Large Sample Study on Paroxysmal Kinesigenic Dyskinesia: Genotype-Phenotype Analysis and Diagnosis Recommendations

    L. Cao, XJ. Huang, SG. Wang, WT. Tian, HD. Tang, JY. Shen, C. Zhang, ZY. Zhu, FX. Zhan, XQ. Che, SD. Chen, XL. Liu, T. Wang, YQ. Xu, HW. Gui, L. Zheng, L. Wu, TY. Rong, M. Zhang, Y. Wang, GH. Bi, WG. Tang, BS. Tang, XM. Yin, X. Mao, S. Zeng, JL. Wang, J. Li, Q. Liu, XN. Guo, CY. Wang, W. Lu, RX. Zhang, XR. Liu, Y. Zhang, ZG. Liu, GH. Zhao (Shanghai, China)

    Objective: By analyzing nationwide large samples provided by China Paroxysmal Kinesigenic Dyskinesia Association(CPKDA), this study is attempted to summarize the clinical phenotypes and genetic features…
  • 2019 International Congress

    Quantifying gait parameters in Parkinson’s disease patients who do and do not exhibit freezing of gait.

    K. Kwei, A. De-La Mora, D. Payne, D. Tomishon, S. Agrawal, N. Vanegas-Arroyave (New York, NY, USA)

    Objective: To determine whether gait parameters in PD patients who have freezing of gait (FOG) differ from those who do not. Background: FOG is a…
  • 2019 International Congress

    How Commonly Does Parkinson’s Disease Present with Dystonia?

    P. Popa, C. Brown, C. Henchcliffe, H. Sarva (New York, NY, USA)

    Objective: To review dystonia as the presenting feature of Parkinson’s disease (PD). Background: Dystonia in PD is most commonly described as a levodopa complication. It…
  • 2019 International Congress

    7,8- Dihydroxyflavone prevents 3-NitropropionicAcid (3-NP)-induced Striatal Toxicity by Modulating the TrkB receptor and Microglial Activation Pathway

    S. Ahmed, M. Kwatra, VGM. Naidu (Kamrup, India)

    Objective: Hungtion’s disease (HD) is an autosomal governing neurodegenerative disorder caused by production of mutant hungtingtin(Htt) protein followed by death of the GABAergic neurons in…
  • 2019 International Congress

    MRI, Clinical, and Neuropathological Findings after Bilateral Intra-striatal Administration of rAAV5-miHTT in Non-human Primates

    J. Higgins, B. Blits, L. Spronck, A. Valles-Sanchez, M. Evers, S. van Deventer, P. Konstantinova, M. de Haan (Lexington, MA, USA)

    Objective: To assess the effects of intra-striatal administration of a huntingtin protein (HTT) lowering gene therapy in macaca fascicularis non-human primates (NHP). Background: The aggregation…
  • 2019 International Congress

    Multimodal characterization of the visual network in Huntington’s disease

    O. Odish, S. Gregory, I. Mayer, J.. Mills, E. Johnson, R. Scahill, J. Rothwell, G. Rees, J. Long, S. Tabrizi, R. Roos, M. Orth (Leiden, Netherlands)

    Objective: To examine the relationship between structural organization, functional processing and task performance of the visual system in a cohort of Huntington’s disease (HD) gene-mutation…
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