Parkinson’s disease-associated mutations of PLA2G6 alters the membrane dynamics and α-synuclein stability
Objective: To investigate the mechanism of α-synuclein (α-Syn) aggregation. Background: PLA2G6 has been isolated as the gene responsible for an autosomal recessive form of Parkinson’s…Glabellar tap predicts dopamine transporter deficiency in parkinsonism
Objective: The objective of this study was to investigate the association between glabellar tap findings with nigrostriatal dopamine function in patients with unclear parkinsonism. Background:…Comorbid Parkinson’s disease in a Korean patient with Alexander’s disease
Objective: We report a unique case of genetically diagnosed Alexander's disease comorbid, with clinically diagnosed Parkinson's disease. Background: Alexander disease is a neurological disease, that causes…Levodopa-carbidopa intestinal gel infusion: a video analysis of long-term effect on gait and posture
Objective: To investigate the long-term effect of levodopa-carbidopa intestinal gel (LCIG) on gait and posture by means of both clinical and objective measures in Parkinson’s…Cortical thickness analysis in Parkinson’s disease with urinary symptoms
Objective: This study aimed to identify the significant region which can be related to urinary symptoms in Parkinson’s disease using correlation analysis between non-motor symptoms…Awareness of Levodopa/Carbidopa spacing with meals in patients of Idiopathic Parkinson’s disease – Insights from an Indian Parkinson’s Registry
Objective: Food interferes with gastrointestinal absorption of levodopa which requires spacing with meals. Study evaluated how many patient were spacing levodopa correctly, its effect on…Posterior cortical atrophy (PCA) attributable to corticobasal degeneration
Objective: Introduction: PCA is a clinico-radiological syndrome characterized by progressive decline in visual processing and other posterior cognitive functions, relatively intact memory and language in…A Thorough QT Study of Apomorphine Sublingual Film in Patients With Parkinson’s Disease Complicated By “OFF” Episodes
Objective: To assess the effect of apomorphine sublingual film (APL130277; APL) on the QT interval in patients with Parkinson’s disease (PD) and “OFF” episodes participating…Identification of potential new genes involved in autosomal recessive forms of Parkinson’s disease
Objective: The aim of the work is to identify new genes involved in autosomal recessive (AR) early-onset (EO, >40 years) Parkinson disease (PD), using consanguineous…Lip movement contribution in speech production of persons with Parkinson’s Disease
Objective: Lip movements contribute to communication by producing labial sounds, conveying facial expression and aiding visually in speech perception. This study planned to understand lip-movements…
