The Oral Metagenome and Metatranscriptome of Early Stage Parkinson’s Disease and their Relationship with Clinical and Functional Outcome Measures of Motor and Nonmotor Function
Objective: To identify sensitive and specific biomarkers of changes in the oral microbiome of subjects with early stage Parkinson’s Disease and relate these to clinical,…Investigating the cellular role of LRRK2 in the immune system
Objective: The objective of this project is to investigate the effect of Leucine Rich-Repeat Kinase 2 (LRRK2) dysfunction in the signalling mechanisms in macrophages and…Postural alterations in patients with Progressive Supranuclear Palsy
Objective: Biomechanical assessment of postural imbalance in patients with Progressive Supranuclear Palsy (PSP) Background: PSP is a neurodegenerative disease characterized by early impairment of balance…Cortical FDG-PET patterns predict long-term motor progression and disability milestones in Parkinson’s disease
Objective: To evaluate the accuracy of single-subject FDG-PET in predicting motor and cognitive long-term progression in Parkinson's disease Background: The progression of Parkinson's disease is…Risk of Parkinson’s in idiopathic anosmia
Objective: To identify markers of increased risk of Parkinson’s in a cohort of individuals with idiopathic anosmia Background: Smell loss (anosmia) is a common finding…Evaluation of Clinical Peculiarities of Violations of Vertical Vision in Patients with Parkinson’s Disease
Objective: To study vertical oculomotor reflexes(VOR) and the state of the functional system "eyelid" in patients with Parkinson's disease. Background: Parkinson's disease (PD) is a common…Postural instability secondary to hypoxic injury to the bilateral globus pallidi
Objective: To describe a case of post-hypoxic postural instability associated with bilateral internal globus pallidi (GP) infarcts. Background: A variety of movement disorders, including parkinsonism,…A First in Human Study of PBT434, a Novel Small Molecule Inhibitor of Alpha-Synuclein Aggregation
Objective: To evaluate the safety, tolerability and pharmacokinetics of PBT434 in healthy volunteers. Background: PBT434 is a novel, small molecule inhibitor of alpha-synuclein aggregation. In…Neuroprotective effect of crocus sativus in lead-induced dopaminergic neurotoxicity in Meriones shawi: A possible link with Parkinson’s disease
Objective: In this study, we have evaluated, in one hand, the neurotoxic effect of Pb (25 mg / kg B.W i.p) for three consecutive days…Association between quality of life and physical functions in patients with idiopathic Parkinson’s disease
Objective: The aim was to investigate the association between health-related quality of life and physical functions in the patients with idiopathic Parkinson's disease (PD). Background:…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.