Influence of motor fluctuations duration, levodopa dose and duration of use in efficacy responses of Parkinson’s disease patients: post-hoc analysis from combined BIPARK-I and II.
Objective: To evaluate the impact of motor fluctuations (MF) duration, levodopa dose and levodopa duration of use (LDU) in efficacy responses of levodopa-treated Parkinson’s Disease…A randomized, placebo-controlled, double-blind clinical study in Japan of Opicapone treatment for Parkinson’s Disease -Comfort-PD Study part 1
Objective: To investigate efficacy and safety of two doses of Opicapone (OPC) compared to placebo administered once daily for 14 to 15 weeks to Japanese…Using cognitive computing to identify existing drugs with potential to stabilize mitophagy pathways associated with Parkinson’s Disease
Objective: We applied IBM Watson for Drug Discovery (WDD), a cognitive computing platform that uses natural language processing, to identify compounds with the potential to…Polysomnographic features of Spinocerebellar Ataxia type 3 – a case report
Objective: To describe, through a case report, the range of abnormal sleep patterns of Spinocerebellar Ataxia type 3 (SCA3). Background: SCA3 is a progressive neurodegenerative…Lower urinary tract symptoms and urodynamic findings in SCAs
Objective: Characterization of urinary dysfunctions in SCAs is needed not only for the understanding of SCAs but also for the correct diagnosis in patients with…Gait in Spinocerebellar Ataxia Type12 (SCA-12)
Objective: The aim of our study was to evaluate the spatial and temporal parameters of gait in SCA12 patients and to compare it with healthy…The severity of motor dysfunctions and autonomic dysfunctions are not correlated in multiple system atrophy
Objective: Although it is well known that patients with multiple system atrophy (MSA) cerebellar dominant type (MSA-C) show severe autonomic dysfunction, the relationship between autonomic…Steroid responsive chorea in Moyamoya disease: illustrative cases
Objective: To report the rapid reduction of disabling chorea in two cases of pediatric Moyamoya disease with pulse steroid therapy. Background: The common clinical presentation…Dancing larynx syndrome associated with trigeminal neuralgia secondary to multiple sclerosis
Objective: To describe a rare a case of a patient who developed “dancing larynx”-like syndrome after gamma knife radiation for trigeminal neuralgia (TN) associated with…Apomorphine induced hemolytic anemia: A case report and literature review
Objective: To present a case of apomorphine induced hemolytic anemia Background: Drug induced immune hemolytic anemia (DIIHA) is a potentially lethal adverse reaction; It has…
