MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Adult-onset stereotypy — An atypical presentation of frontotemporal dementia

    C. Walsh, L. Brennan, J. Ratliff (Philadelphia, PA, USA)

    Objective: Describe a case of adult-onset stereotypy with abulia. Background: Stereotypy is a non-goal directed but distractible behavior repeated continuously. While common in the pediatric…
  • 2019 International Congress

    Translating Preclinical Data to a Human Equivalent Dose for AMT-130 AAV Gene Therapy for Early Manifest Huntington’s Disease

    M. Evers, M. de Haan, A. Valles-Sanchez, E. Sawyer, S. Gill, R. Roos, S. van Deventer, P. Konstantinova, J. Higgins (Amsterdam, Netherlands)

    Objective: To extrapolate the human equivalent dose (HED) for a Phase I/II clinical trial in adults to explore the safety, tolerability, and efficacy of striatally-administered…
  • 2019 International Congress

    Prevalence of Huntington’s Disease in Sardinia, Italy

    A. Muroni, MR. Murru, T. Ercoli, V. Melas, E. Casaglia, M. Melis, E. Cocco, G. Defazio (Cagliari, Italy)

    Objective: We have performed a service-based epidemiological analysis extended to the population residing in Sardinia. The socio-cultural isolation of this large Mediterranean island makes genetic…
  • 2019 International Congress

    Usefulness of Heart Rate Variability to Identify the Risk of Falling in Huntington’s Disease

    C. Terroba-Chambi, D. Vigo, M. Merello (Buenos Aires, Argentina)

    Objective: To evaluate the relationship between the HRV and the risk of falling in HD patients. Background: Huntington's disease (HD) patients have a high prevalence…
  • 2019 International Congress

    Parkinson Kinetigraph – does it change the management of PD patients?

    F. Bergquist, A. Cvejtkovic, AC. Sjöström, S. Wallerstedt (Gothenburg, Sweden)

    Objective: This pragmatic randomized open trial evaluated if the information from a Parkinson Kinetigraph (PKG) recording changed the management of PD patients at a visit…
  • 2019 International Congress

    Incidence of treatment-emergent adverse events in Parkinson’s disease patients according to baseline disease severity: post-hoc analysis from double-blind combined BIPARK-I and II data

    R. Costa, A. Lees, J. Ferreira, O. Rascol, F. Stocchi, H. Gama, D. Magalhães, J. Rocha, P. Soares-da-Silva (Coronado, Portugal)

    Objective: To evaluate the incidence of treatment-emergent adverse events (TEAEs) in levodopa-treated Parkinson’s Disease (PD) patients with motor fluctuations and taking opicapone (OPC). Background: OPC…
  • 2019 International Congress

    Efficacy, Safety and Tolerability of Tavapadon in Subjects With Early Stage Parkinson’s Disease

    D. Gray, R. Riesenberg, J. Werth, Y. Zhang, M. Versavel, S. Duvvuri (Boston, MA, USA)

    Objective: To evaluate the efficacy and safety of tavapadon (formerly known as PF-06649751) in subjects with early stage Parkinson’s disease. Background: Tavapadon is a potent,…
  • 2019 International Congress

    Duration of rimabotulinumtoxinB action in the treatment of adult sialorrhea

    S. Isaacson, M. Lew, F. Pagan, R. Pahwa, D. Chary, T. Clinch (Boca Raton, FL, USA)

    Objective: To assess the duration of rimabotulinumtoxinB action in the management of sialorrhea. Background: In neurological disorders, sialorrhea (drooling) is both prevalent and problematic. Local…
  • 2019 International Congress

    Medical management of primary hemifacial spasm

    G. Kumar, D. Kaur, A. Singh (Patna, India)

    Objective: The purpose of this study is to evaluate the effect of various anti-epileptic drugs(AED) in the medical management of HFS in patients who cannot…
  • 2019 International Congress

    Safinamide: real world evidence in Toledo´s Movement Disorders Unit

    N. López-Ariztegui, MI. Morales-Casado, JC. Segundo-Rodríguez, A. Avila-Fernández, N. García-Alvarado, J. Pérez-Matos (Toledo, Spain)

    Objective: We present a prospective observational-real life study about the use of safinamide in Movement Disorders Unit´s patients. Background: The gold standard of pharmacological treatment…
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