Synaptic function in Parkinson’s disease associated with GBA mutations
Objective: To investigate the pathological substrate of impaired cognition in Parkinson’s disease (PD) associated with glucocerebrosidase (GBA) mutation. Background: Mutations in glucocerebrosidase gene (GBA), originally…Clinical patterns of gait freezing in Parkinson’s disease and their response to interventions: an observer-blinded study
Objective: To evaluate the occurrence and severity of FOG in provoking situations during a standard video-recorded walking task. To use this method to compare the effects…The effect of coexistent neurodegenerative disorders on the clinical features of idiopathic normal pressure hydrocephalus
Objective: To determine the prevalence of neurodegenerative disorders in idiopathic normal pressure hydrocephalus (iNPH) and their effects on the clinical features of iNPH. Background: To…Baseline hyposmia and RBD symptoms are associated with faster, but differential, cognitive decline at 2 years in the PPMI study
Objective: To explore the potential role of baseline hyposmia and RBD symptoms on progression of cognitive decline at 2 years. Background: Cognitive decline in PD…Zonisamide ameliorates levodopa-induced dyskinesia via striatal cholinergic system in a rat model of Parkinson’s disease
Objective: To investigate the difference in results according to the mode of levodopa administration and the effect of zonisamide (ZNS) on striatal cholinergic system, we…Cognitive event related potentials as biomarker of non-motor phenotypes in Parkinson’s Disease
Objective: This research aimed to study the specific changes in cognitive event related potentials (ERP) in patients with different non-motor subtypes of Parkinson’s disease (PD).…STN-DBS programing for dyskinesia: a case report
Objective: To investigate the effect of STN stimulation on different types of dyskinesia and programming strategy. Background: Long-term use of levodopa or dopamine agonists often…Machine learning classifiers and subjective vocal perception of Parkinson’s disease patients and healthy control
Objective: To identify machine learning classifiers and to assess the acoustic differences between PD patients and healthy control (HC) and the relations between objective and…Preferred place of death (PPOD) in PD, PSP and MSA
Objective: To ascertain whether people with PD, PSP and MSA have a PPOD Background: Achieving a PPOD is felt to be an important factor in…PARKINSON DISEASE HAMPERS PARTICIPATION IN THE CIVIC RESPONSIBILITY OF VOTING: a study of barriers to expression of a fundamental human right
Objective: To determine the impact of PD on the participation of persons with Parkinson disease in the recently concluded national elections in Lagos,Nigeria, and explore…
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