Quantification of 123I-ioflupane Striatal Uptake and Individual Patient Diagnostic Predictions: Degenerative Parkinson’s disease, Non-Degenerative Parkinsonism and Tremor Disorders
Objective: To develop a fully automated quantitative method to analyse routinely acquired 123I-ioflupane (DaTSCAN) data to aid diagnostic predictions in patients with Parkinson’s disease, non-degenerative…Quantitative Susceptibility Mapping for Differential Diagnosis of Degenerative Parkinsonisms: A Comparison with Morphometric Indexes
Objective: To use a multimodal MRI approach for differential diagnosis of patients with degenerative parkinsonisms, comparing the diagnostic accuracy of Quantitative Susceptibility Mapping (QSM) data…Intrinsic Remodeling of the Fovea is Correlated with Contrast Sensitivity Loss in Parkinson’s Disease
Objective: The aim of the study was to determine a technical parameter of foveal pathology that is best suited for discriminating Parkinson’s disease (PD) eyes…Levodopa Changes Functional Connectivity Patterns in Subregions of the Primary Motor Cortex in Patients with Parkinson’s Disease
Objective: To investigated functional connectivity pattern changes in M1 subregions and relationships to improved clinical symptoms following levodopa administration. Background: The primary motor cortex (M1)…Prefrontal cortical activity and the control of walking in people with freezing of gait
Objective: To investigate the influence of freezing of gait (FoG) on automaticity of walking in people with Parkinson’s disease (PD). Background: A hallmark of healthy…A reliable measure of rigidity with a novel robotic device
Objective: The objective of our study was to objectively measure the rigidity in PD patients, using a recently validated robotic device. Background: Rigidity is one…Bilateral double beta peaks in a PD patient with STN electrodes
Objective: We aimed to record LFPs of the subthalamic nucleus (STN) from a PD patient with a new implantable pulse generator (IPG), which is capable…Impulse Control Behaviours in People with Parkinson’s Disease: Findings from the Parkinson’s Disease Real-World Impact Assessment (PRISM) Study
Objective: Presence of impulse control behaviour (ICB) was assessed in PRISM, a European survey of people with Parkinson’s disease (PwP) and their care-partners. Background: Impulse…Orthostatic hypotension in Parkinson’s disease
Objective: We aimed to identify whether orthostatic hypotension (OH) is a prodromal marker of Parkinson’s disease (PD) or a symptom of later disease. Background: Many…Frequency of Nonmotor Symptoms Parkinson’s Disease in the Early Morning off Period
Objective: To increase early recognition of these symptoms, by investigating the frequency of nonmotor symptoms (NMS) in patients with Parkinson's disease (PD) who have early…
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