Regional cortical thickness alterations in PD patients with cognitive impairment
Objective: To evaluate the cortical thickness alterations in cognitively impaired patients with PD (PD-CI) in a comparative study with cognitively normal patients with PD (PD-CN)…Both Symptomatic and Asymptomatic Orthostatic Hypotension is Associated with Cognitive Decline Over Time in Parkinson’s Disease
Objective: To compare cognitive changes over time between Parkinson's disease (PD) patients with orthostatic hypotension (OH) and without OH, and between those with symptomatic OH…The feasibility of cognitive telerehabilitation in patients with Parkinson´s disease: The pilot data
Objective: The aim of this study was to focus on the feasibility and potential benefits of cognitive telerehabilitation (CTR) in patients with Parkinson´s disease (PD).…The relationship between neuromelanin-sensitive MRI, [123I] meta-iodobenzylguanidine scintigraphy and cognition, in patients with Parkinson’s disease
Objective: We investigate the relationship between the contrast ratio of locus coeruleus (LC-CR) in neuromelanin-sensitive MRI(NMI), MIBG scintigraphy, and cognition/hallucination, in patients with Parkinson’s disease.…An introduction to the Global Parkinson’s Genetics Program (GP2)
Objective: Expanding the current understanding of the genetic architecture of Parkinson’s disease (PD), accelerate discovery and validation of novel disease-causing genetic mutations and provide training…Apolipoprotein E ε4 and risk of freezing of gait in early Parkinson’s disease
Objective: To investigate the association between Apolipoprotein E (APOE) genotype and freezing of gait (FOG) in Parkinson’s disease (PD). Background: This cohort study using the…A novel likely pathogenic SNCA variant associated with Parkinson’s disease
Objective: To report a novel SNCA likely pathogenic variant. Background: The A53T mutation in the SNCA gene, encoding alpha-synuclein (a-syn), was the first established genetic…mRNA level and variants of the SCARB2 gene in the pathogenesis of Parkinson’s disease
Objective: The aim was to test an association of rs6812193 and rs8475 of the SCARB2 gene with Parkinson’s disease (PD) in case–control study in Russia.…Glucocerebrosidase Deficiency Mediates Propagation of Protein Aggregation via Extracellular Vesicle Dysregulation
Objective: Investigate a role for GBA in accelerating the spread of protein aggregates via extracellular vesicles (EVs). Background: Parkinson’s disease (PD) progression correlates with temporo-spatial…A novel peptide reduces α-synuclein levels and neurodegeneration in cell, invertebrate, and mammalian models of Parkinson’s disease
Objective: To identify and test the effectiveness of a novel peptide to reduce α-synuclein levels and neurodegeneration in cell and animal models of Parkinson’s disease…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.