MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Pharmacokinetics of Levodopa in patients with Parkinson’s disease: Efforts toward a predictive model

    N. Nishikawa, H. Iwaki, T. Shiraishi, Y. Mukai, Y. Takahashi, N. Hattori (Kodaira, Japan)

    Objective: Our aim was to explore correlations between the pharmacokinetics of levodopa (LD) and clinical manifestation in patients with Parkinson’s disease (PD). Our goal was…
  • MDS Virtual Congress 2020

    Indication and long-term outcome of device-aided therapies in advanced Parkinson’s disease

    M. Shiraishi, F. Maki, M. Kato, Y. Morosawa, I. Takumi, K. Isahaya, N. Sasaki, Y. Hasegawa (Kawasaki, Japan)

    Objective: We aimed to demonstrate the real world differences in a single center. Background: Number of deep brain stimulation (DBS) and levodopa-carbidopa continuous infusion gel…
  • MDS Virtual Congress 2020

    Identification and characterization of anti-prionic compounds that disassemble αSyn prions as a novel therapeutic approach for synucleinopathies

    D. Willbold, M. Sevenich, W. Hoyer, J. Mohrlüder, A. Willuweit (Jülich, Germany)

    Objective: Stabilization of monomeric α-synuclein protein (αSyn) by transient and high-affinity binding ligands is a novel and highly innovative anti-prionic treatment strategy for synucleinopathies .…
  • MDS Virtual Congress 2020

    Relationship between REM sleep without atonia and sleep architecture in multiple system atrophy

    Y. Saitoh, M. Miyazaki, A. Tsuru, Y. Takahashi (Kodaira, Tokyo, Japan)

    Objective: To investigate whether REM sleep without atonia (RWA) is associated with sleep architecture in patients with multiple system atrophy (MSA). Background: In MSA patients,…
  • MDS Virtual Congress 2020

    Correlations between amantadine usage, gait, and cognition in PSP: a post hoc analysis of the davunetide trial

    M. Dale, B. Brumbach, A. Hiller (Portland, OR, USA)

    Objective: Amantadine anecdotally improves gait and balance in PSP, potentially by increasing alertness, but there are no definitive data to support this observation. We investigated…
  • MDS Virtual Congress 2020

    Temporhythmal Correction: The New Way of Therapy and Diagnostic Secondary Vascular Parkinsonism

    D.T Akramova (Tashkent, Uzbekistan)

    Objective: It is known that, in vascular parkinsonism (VP) and Parkinson’s disease (PD) it is observed shortening of steps, bradikinesia, oligokinesia, gait disorders and also…
  • MDS Virtual Congress 2020

    May Safinamide have a Role in Atypical Parkinsonism? A Retrospective Study in Clinical Practice

    F. Rodríguez Jorge, A. Beltrán Corbellini, J.L Chico García, P. Parra Díaz, P. Pérez Torre, B. Baena Álvarez, I. Parées Moreno, J.L López-Sendón, J.C Martínez Castrillo, A. Alonso Cánovas, S. Fanjul Arbós (Madrid, Spain)

    Objective: To evaluate efficacy and safety of safinamide in atypical parkinsonian syndromes. Background: Safinamide (50-100 mg) has proved efficacy as an add-on treatment to levodopa…
  • MDS Virtual Congress 2020

    Mutations of COX20 affect the assembly and function of complex IV causing early onset ataxia, dystonia and neuropathy

    Y.M Liu, P.Z Li, DD. Guo, H.B LV, Y.L Zhang (Jinan, China)

    Objective: To find the causes of an early onset complex movement disorder in two sisters from a non-consanguineous family, and confirm the COX20 variants responsible for such mitochondrial…
  • MDS Virtual Congress 2020

    Clinical progression of Parkinson’s disease: insights from the NINDS common data elements

    M. Lewis, E. Harkins, E. Lee, C. Stetter, B. Snyder, T. Corson, G. Du, L. Kong, X. Huang (Hershey, PA, USA)

    Objective: To synchronize data collection, the National Institute of Neurological Disorders and Stroke recommended Common Data Elements (CDEs) for use in Parkinson’s disease (PD) research.…
  • MDS Virtual Congress 2020

    Home validation of a smartphone-based tapping task to assess medication responsiveness in Parkinson’s disease

    S. Broeder, R. Bussels, S. Vanden Schoor, G. Roussos, J-J. Orban deXivry, A. Nieuwboer (Leuven, Belgium)

    Objective: To validate a timed tapping task (TTT) on a smartphone to ascertain differences in OFF- and ON-phases in Parkinson’s disease (PD) in the home…
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