TET2-mediated Cdkn2A DNA hydroxymethylation in dopaminergic neuronal injury of Parkinson’s disease
Objective: Studies have shown that 5-hmC modification is the reverse reaction of DNA methylation, and that this process is regulated by TET family hydroxylases, but…Salivary proteome in Parkinson’s disease
Objective: The purpose of this paper is to characterize salivary proteome in PD comparing to healthy subjects using proteomic approach. Background: Parkinson’s disease (PD) is…Sex-related longitudinal change of motor features and biological biomarkers in early Parkinson’s disease from the PPMI cohort
Objective: We aim to describe sex-related longitudinal changes in (1) motor features and motor aspects of experiences of daily living and (2) biologic measures as…Free Water in Corpus Callosum is Sensitive to Parkinson’s Disease-related Cognitive Decline
Objective: The objective of this study was to determine if the novel diffusion metric, free water (FW), from two-tensor modeling could sensitively identify microstructural alterations…Tractography of the corticospinal tract in Parkinson’s disease. How does diffusion values vary along tract segments?
Objective: To assess diffusion tensor imaging differences between PD patients and healthy controls in 8 corticospinal tract segments. Background: Parkinson’s disease (PD), despite having motor and…Aberrant resting-state functional connectivity in cognitively unimpaired patients with Parkinson´s disease and freezing of gait
Objective: To ascertain the pattern of functional connectivity in PD patients with and without FOG in the absence of cognitive impairment Background: Freezing of gait…Leveraging patient-specific models to optimize DBS monopolar review
Objective: The objective of this study was to determine if patient-specific anatomical imaging can be leveraged to optimize monopolar review. Background: Parkinson’s disease (PD) is…Automated pattern based classification in neuropathology proven parkinsonism
Objective: In patients with parkinsonism and uncertain differential diagnosis, an automated image-based algorithm can help to distinguish idiopathic Parkinson’s disease (IPD) from atypical parkinsonian syndromes…Utilization of a Visualization Software Tool for Deep Brain Stimulation Programming in a Subset of Subjects with Parkinson’s Disease Who Participated in the INTREPID Randomized Clinical Trial
Objective: This report will describe the utilization and parameters associated with the use of a new visualization tool for Deep Brain Stimulation (DBS) programming in…Loss of cortical inhibition in Parkinson’s disease
Objective: To evaluate motor cortex inhibition at different stages of Parkinson’s disease (PD). Background: In PD, striatal dopamine depletion produces profound alterations in the neural…
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