Cortical pathology in Glucocerebrosidase mutation carriers with anxiety: An MRI study
Objective: To employ Magnetic Resonance Imaging (MRI) and investigate structural pathology in the cortex of Glucocerebrosidase (GBA) gene mutation carriers. Background: Mutations in the GBA…Genetic risk scores and hallucinations in Parkinson’s disease patients
Objective: To examine the overlap of genetic architecture for Alzheimer’s disease (AD), schizophrenia (SZ), and PD with the genetic architecture for the occurrence of hallucinations…Interest of multiplex ligation-dependent probe amplification assay to identify pathogenic mutations in Parkinson’s disease patients
Objective: To evaluate the interest of the MLPA (Multiplex Ligation-dependent Probe Amplification) commercially available kit in the genetic testing in Parkinson’s disease (PD). Background: PD…TET2-mediated Cdkn2A DNA hydroxymethylation in dopaminergic neuronal injury of Parkinson’s disease
Objective: Studies have shown that 5-hmC modification is the reverse reaction of DNA methylation, and that this process is regulated by TET family hydroxylases, but…Salivary proteome in Parkinson’s disease
Objective: The purpose of this paper is to characterize salivary proteome in PD comparing to healthy subjects using proteomic approach. Background: Parkinson’s disease (PD) is…Sex-related longitudinal change of motor features and biological biomarkers in early Parkinson’s disease from the PPMI cohort
Objective: We aim to describe sex-related longitudinal changes in (1) motor features and motor aspects of experiences of daily living and (2) biologic measures as…Free Water in Corpus Callosum is Sensitive to Parkinson’s Disease-related Cognitive Decline
Objective: The objective of this study was to determine if the novel diffusion metric, free water (FW), from two-tensor modeling could sensitively identify microstructural alterations…Tractography of the corticospinal tract in Parkinson’s disease. How does diffusion values vary along tract segments?
Objective: To assess diffusion tensor imaging differences between PD patients and healthy controls in 8 corticospinal tract segments. Background: Parkinson’s disease (PD), despite having motor and…Aberrant resting-state functional connectivity in cognitively unimpaired patients with Parkinson´s disease and freezing of gait
Objective: To ascertain the pattern of functional connectivity in PD patients with and without FOG in the absence of cognitive impairment Background: Freezing of gait…Leveraging patient-specific models to optimize DBS monopolar review
Objective: The objective of this study was to determine if patient-specific anatomical imaging can be leveraged to optimize monopolar review. Background: Parkinson’s disease (PD) is…
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