Possible correlations between symptoms suggesting gastroparesis and dyskinesias in advanced Parkinson’s disease
Objective: The objective was to describe the spectrum of gastrointestinal complaints in a large cohort of patients with advanced Parkinson’s Disease (APD), who were repeatedly…Using machine learning methods to explore gait features associated with freezing of gait in Parkinson’s Disease
Objective: To find hidden gait patterns associated with freezing of gait (FoG) in Parkinson’s disease (PD) by using machine learning techniques on the spatial and…Motor onset of Parkinsonʼs disease: Is there a somatotopic pattern?
Objective: To study the clinical onset and progression of motor manifestations in different body regions in early PD patients. Background: The vulnerability of the nigrostriatal…Alpha synuclein BAC transgenic mice as a preclinical model for disease-modifying therapies in Parkinson’s disease
Objective: The aim of this study is to make preclinical mice models for disease-modifying therapies in Parkinson's disease. Background: The prodromal stage of Parkinson's disease…Increased risk of Parkinson’s disease in patients with schizophrenia spectrum disorders
Objective: To investigate the coincidence of Parkinson’s disease (PD) and schizophrenia spectrum disorders (SCD). Background: PD is characterized by a progressive loss of mesostriatal dopamine…Effect of Levodopa-Carbidopa Intestinal Gel Versus Optimized Medical Treatment on Dyskinesia in Advanced Parkinson’s Disease Patients: Final Results of the Randomized 12-Week DYSCOVER Study
Objective: This study evaluated the effectiveness of LCIG versus optimized medical treatment (OMT) on the duration and severity of dyskinesia in aPD patients. Background: Approximately…Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Impact of Concomitant Antiemetics and Dopamine Agonists on Nausea and Vomiting
Objective: Analyze effect of concomitant antiemetics and dopamine agonists (DA) on nausea and vomiting (N/V) in patients receiving apomorphine sublingual film (APL-130277; APL) for on-demand…The Association of Taichi to Delayed Progression of Parkinson’s Disease
Objective: To discover the effect of physical exercise on motor and non-motor symptoms in Parkinson’s disease (PD), and to explore whether physical exercise could delay…Morphological changes of retina in patients with Parkinson’s disease and the role of α-synuclein in retinal damage
Objective: To analyze the characteristics of retinal structural changes in patients with PD by the noninvasive technology of OCT. Demonstrate the role of α-syn in pathological changes of…A Patient with Gait Disturbance Caused by Parkinson’s Disease: A Case Report
Objective: It is well known that mental simulation of movement in the brain can facilitate motor rehabilitation. Our hypothesis is: can a direct, sequential stimulation…
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